Characteristics of Induced Ventricular Fibrillation Cycle Length in Symptomatic Brugada Syndrome Patients

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著者

    • HIRATSUKA Atsushi
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
    • SHIMIZU Akihiko
    • Faculty of Health Science, Yamaguchi University Graduate School of Medicine
    • UEYAMA Takeshi
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
    • YOSHIGA Yasuhiro
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
    • DOI Masahiro
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
    • OHMIYA Toshihide
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
    • YOSHIDA Masaaki
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
    • FUKUDA Masakazu
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
    • MATSUZAKI Masunori
    • Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine

抄録

<b><i>Background:</i></b> Limited information is available on the ventricular fibrillation (VF) spectrum in Brugada syndrome (BS) patients. We clarified differences in the VF cycle length (CL) using fast-Fourier transformation (FFT) analysis in symptomatic and asymptomatic BS patients. <b><i>Methods and Results:</i></b> VF was induced by pacing from the right ventricular (RV) apex and/or RV outflow tract (RVOT) for >8s. A 4096-point FFT analysis of results from 28 male BS patients (51.1±13.7 years old) was performed. Dominant frequency (DF) from phases 1 (4s) to 6 was obtained at 2-s intervals. The average DF from surface and intracardiac electrograms (ECG: DF<sub>ECG</sub>; ICE: DF<sub>ICE,</sub>, respectively) was compared between symptomatic and asymptomatic patients. Symptomatic patients had a significantly shorter effective refractory period at a CL of 600ms at the RVOT than asymptomatic patients. DF<sub>ECG</sub> significantly increased with phase (5.64±0.32Hz in phase 1 to 6.16±0.52Hz in phase 6) and was significantly higher in symptomatic patients than in asymptomatic patients. DF<sub>ICE</sub> had the same characteristics as DF<sub>ECG</sub>. <b><i>Conclusions:</i></b> Induced VF in BS patients can be characterized using FFT analysis. Our data support the hypothesis that symptomatic patients have a significantly shorter VF CL than asymptomatic patients. (<i>Circ J</i> 2012; <b>76:</b> 624-633)<br>

収録刊行物

  • Circulation journal : official journal of the Japanese Circulation Society

    Circulation journal : official journal of the Japanese Circulation Society 76(3), 624-633, 2012-02-25

    一般社団法人 日本循環器学会

参考文献:  33件中 1-33件 を表示

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10030129902
  • NII書誌ID(NCID)
    AA11591968
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13469843
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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