Dabigatran in Clinical Practice for Atrial Fibrillation With Special Reference to Activated Partial Thromboplastin Time
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- Suzuki Shinya
- The Cardiovascular Institute
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- Otsuka Takayuki
- The Cardiovascular Institute
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- Sagara Koichi
- The Cardiovascular Institute
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- Matsuno Shunsuke
- The Cardiovascular Institute
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- Funada Ryuichi
- The Cardiovascular Institute
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- Uejima Tokuhisa
- The Cardiovascular Institute
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- Oikawa Yuji
- The Cardiovascular Institute
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- Yajima Junji
- The Cardiovascular Institute
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- Koike Akira
- The Cardiovascular Institute
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- Nagashima Kazuyuki
- The Cardiovascular Institute
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- Kirigaya Hajime
- The Cardiovascular Institute
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- Sawada Hitoshi
- The Cardiovascular Institute
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- Aizawa Tadanori
- The Cardiovascular Institute
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- Yamashita Takeshi
- The Cardiovascular Institute
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Background: The distribution of activated partial thromboplastin time (APTT) in nonvalvular atrial fibrillation (NVAF) patients under dabigatran therapy remains to be clarified. Methods and Results: The study population was 196 NVAF patients who were treated with dabigatran in 2011 (126 with 220mg/day). The APTT values showed a wide distribution among the patients, especially in those with a reduced dose, who seemed to show a high value even in patients without contraindications. Conclusions: We found a wide distribution of APTT in NVAF patients under dabigatran treatment. High APTT might help screen for bleeding risks among patients under dabigatran, but requires future investigation. (Circ J 2012; 76: 755-757)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 76 (3), 755-757, 2012
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205105141888
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- NII論文ID
- 10030130511
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- NII書誌ID
- AA11591968
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- COI
- 1:CAS:528:DC%2BC38XltFKrsb4%3D
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- ISSN
- 13474820
- 13469843
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- PubMed
- 22293451
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 使用不可