Dabigatran in Clinical Practice for Atrial Fibrillation With Special Reference to Activated Partial Thromboplastin Time

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<b><i>Background:</i></b> The distribution of activated partial thromboplastin time (APTT) in nonvalvular atrial fibrillation (NVAF) patients under dabigatran therapy remains to be clarified. <b><i>Methods and Results:</i></b> The study population was 196 NVAF patients who were treated with dabigatran in 2011 (126 with 220mg/day). The APTT values showed a wide distribution among the patients, especially in those with a reduced dose, who seemed to show a high value even in patients without contraindications. <b><i>Conclusions:</i></b> We found a wide distribution of APTT in NVAF patients under dabigatran treatment. High APTT might help screen for bleeding risks among patients under dabigatran, but requires future investigation. (<i>Circ J</i> 2012; <b>76:</b> 755-757)<br>

収録刊行物

  • Circulation journal : official journal of the Japanese Circulation Society

    Circulation journal : official journal of the Japanese Circulation Society 76(3), 755-757, 2012-02-25

    The Japanese Circulation Society

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被引用文献:  3件中 1-3件 を表示

各種コード

  • NII論文ID(NAID)
    10030130511
  • NII書誌ID(NCID)
    AA11591968
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    13469843
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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