Overshoot Phenomena of Respiratory Gas Variables During Exercise Recovery in Cardiac Patients

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<b><i>Background:</i></b> Transient increases (overshoot) in respiratory gas variables have been observed during exercise recovery, but their clinical significance is not clearly understood. Our group evaluated the relationship between the presence of overshoot of respiratory gas variables and the parameters obtained from cardiopulmonary exercise testing (CPX). <b><i>Methods and Results:</i></b> In total, 227 patients with various cardiac diseases underwent CPX. The overshoot phenomena of O<sub>2</sub> uptake (VO<sub>2</sub>), VO<sub>2</sub>/heart rate (O<sub>2</sub>-pulse), and CO<sub>2</sub> output (VCO<sub>2</sub>) were analyzed by respiratory gas analysis during recovery after maximal exercise. The overshoot of VO<sub>2</sub>, O<sub>2</sub>-pulse, and VCO<sub>2</sub> were recognized in 11 (5%), 43 (19%), and 12 (5%) patients, respectively. Compared with the patients without a VO<sub>2</sub> overshoot, those with a VO<sub>2</sub> overshoot had a significantly lower peak VO<sub>2</sub> (12.3±3.7 vs. 17.9±6.2ml·min<sup>-1</sup>·kg<sup>-1</sup>, P=0.003), lower anaerobic threshold (9.4±1.7 vs. 12.4±3.3ml·min<sup>-1</sup>·kg<sup>-1</sup>, P=0.001), higher VE-VCO<sub>2</sub> slope (38.0±5.2 vs. 33.2±9.6, P=0.013), and lower left ventricular ejection fraction (LVEF) (39.9±22.8 vs. 55.8±16.8%, P=0.003). Similar findings were obtained for the patients with an O<sub>2</sub>-pulse overshoot and those with a VCO<sub>2</sub> overshoot. <b><i>Conclusions:</i></b> The overshoot phenomena of respiratory gas variables during recovery after maximal exercise are correlated with impaired cardiopulmonary function during exercise in cardiac patients. (<i>Circ J</i> 2012; <b>76:</b> 876-883)<br>

収録刊行物

  • Circulation journal : official journal of the Japanese Circulation Society

    Circulation journal : official journal of the Japanese Circulation Society 76(4), 876-883, 2012-03-25

    一般社団法人 日本循環器学会

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各種コード

  • NII論文ID(NAID)
    10030131147
  • NII書誌ID(NCID)
    AA11591968
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13469843
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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