Comparison of Contrast Media and Low-Molecular-Weight Dextran for Frequency-Domain Optical Coherence Tomography

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著者

    • OZAKI Yuichi
    • Department of Cardiovascular Medicine, Wakayama Medical University
    • HOSOKAWA Seiki
    • Department of Cardiovascular Medicine, Wakayama Medical University
    • INO Yasushi
    • Department of Cardiovascular Medicine, Wakayama Medical University
    • KUBO Takashi
    • Department of Cardiovascular Medicine, Wakayama Medical University
    • KIMURA Keizo
    • Department of Cardiovascular Medicine, Wakayama Medical University
    • TANAKA Atsushi
    • Department of Cardiovascular Medicine, Wakayama Medical University
    • HIRATA Kumiko
    • Department of Cardiovascular Medicine, Wakayama Medical University

抄録

<b><i>Background:</i></b> Although an intracoronary frequency-domain optical coherence tomography (FD-OCT) system overcomes several limitations of the time-domain OCT (TD-OCT) system, the former requires injection of contrast media for image acquisition. The increased total amount of contrast media for FD-OCT image acquisition may lead to the impairment of renal function. The safety and usefulness of the non-occlusion method with low-molecular-weight dextran L (LMD-L) via a guiding catheter for TD-OCT image acquisition have been reported previously. The aim of the present study was to compare the image quality and quantitative measurements between contrast media and LMD-L for FD-OCT image acquisition in coronary stented lesions. <b><i>Methods and Results:</i></b> Twenty-two patients with 25 coronary stented lesions were enrolled in this study. FD-OCT was performed with the continuous-flushing method via a guiding catheter. Both contrast media and LMD-L were infused at a rate of 4ml/s by an autoinjector. With regard to image quality, the prevalence of clear image segments was comparable between contrast media and LMD-L (97.9% vs. 96.5%, P=0.90). Furthermore, excellent correlations were observed between both flushing solutions in terms of minimum lumen area, mean lumen area, and mean stent area. The total volumes of contrast media and of LMD-L needed for OCT image acquisition were similar. <b><i>Conclusions:</i></b> FD-OCT image acquisition with LMD-L has the potential to reduce the total amount of contrast media without loss of image quality. (<i>Circ J</i> 2012; <b>76:</b> 922-927)<br>

収録刊行物

  • Circulation journal : official journal of the Japanese Circulation Society

    Circulation journal : official journal of the Japanese Circulation Society 76(4), 922-927, 2012-03-25

    一般社団法人 日本循環器学会

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各種コード

  • NII論文ID(NAID)
    10030131374
  • NII書誌ID(NCID)
    AA11591968
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13469843
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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