Detection of Attenuated Plaque in Stable Angina With 64-Multidetector Computed Tomography

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  • Jinzaki Masahiro
    Department of Diagnostic Radiology, Keio University School of Medicine
  • Okabe Teruo
    Cardiology Department, International University of Health and Welfare, Mita Hospital
  • Endo Ayaka
    Cardiopulmonary Division, Keio University School of Medicine
  • Kawamura Akio
    Cardiopulmonary Division, Keio University School of Medicine
  • Koga Seiko
    Department of Diagnostic Radiology, Keio University School of Medicine
  • Yamada Minoru
    Cardiovascular Imaging Laboratory in Research Park, Keio University School of Medicine
  • Fukuda Keiichi
    Cardiopulmonary Division, Keio University School of Medicine
  • Kuribayashi Sachio
    Department of Diagnostic Radiology, Keio University School of Medicine

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Other Title
  • Detection of attenuated plaque in stable angina with 64-multidetector computed tomography: a comparison with intravascular ultrasound
  • – A Comparison With Intravascular Ultrasound –

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Abstract

Background: To clarify multidetector computed tomography (MDCT) findings of attenuated plaque detected by intravascular ultrasound (IVUS). Methods and Results: One hundred and fifty-four patients with stable angina underwent MDCT before IVUS. The attenuated plaque was identified in the targeted artery with IVUS, and the same artery was analyzed with MDCT for the presence of a high density area (HDA) >130 Hounsfield units (HU), and a low density area (LDA) <30HU. A HDA in attenuated plaque was compared with that in calcified plaque. Ten attenuated plaques and 15 calcified plaques were identified in 9 of 154 patients (males=9, 66.2±9.5 years). Eight of the 10 attenuated plaques and all 15 calcified plaques were accompanied with a HDA on MDCT. The HDA ranged from 174 to 667HU (mean 389.0±148.3HU) in the 8 attenuated plaques, and from 545 to 1,205HU (mean 920.9±215.9HU) in 15 calcified plaques. There was a significant difference in CT density of the HDA between the attenuated and calcified plaque (P<0.001). All attenuated plaques contained LDA <30HU in the portions without HDA. Conclusions: MDCT has the ability to demonstrate attenuated plaque as the combination of HDA (approximately 400HU on average) and LDA <30HU. The HDA can be differentiated from calcified plaque by its lower CT density value. (Circ J 2012; 76: 1182-1189)<br>

Journal

  • Circulation Journal

    Circulation Journal 76 (5), 1182-1189, 2012

    The Japanese Circulation Society

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