Cone Beam CT を用いた前立腺がん強度変調放射線治療における Intra-fractional Motion の検討 Intra-fractional Set-up and Organ Motion Errors in Intensity-modulated Radiation Therapy for Prostate Cancer

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<i>Purpose</i>: The aim of this study is to investigate various intra-fractional errors and to determine the appropriate planning target volume (PTV) margins in intensity modulated radiation therapy (IMRT) for prostate cancer. <i>Methods</i>: Ten patients with prostate cancer treated with IMRT between July 2009 and March 2010 were analyzed. PTV was created by adding 4 mm posterior and 7 mm anterior and lateral margins to the clinical target volume (CTV) including prostate and proximal seminal vesicles. Intra-fractional set-up and organ motion errors were measured using cone beam computed tomography (CBCT) images before and after each irradiation. Systematic and random errors were calculated by van Herk and Stroom’s models. <i>Results</i>: Intra-fractional errors of set-up and organ motion were 0.70±0.84 mm and 0.88±0.95 mm in the left-right (L-R), 1.04±0.98 mm and 1.69±1.58 mm in the cranial-coudal (C-C), and 1.08±1.01 mm and 1.91±1.58 mm in the anterior-posterior (A-P) directions, respectively. The errors in the C-C and A-P were significantly larger than those in the L-R (p<0.01). The organ motion errors in the C-C and A-P were significantly larger than the set-up errors (p<0.01). The appropriate PTV margin estimated in this study was 4.73 mm. <i>Conclusions</i>: Intra-fractional errors in all directions were less than 2 mm and required PTV margin in the study was similar to actual posterior margin in our routine practice. It is important to determine intra-fractional errors as well as inter-fractional errors to deliver successful IMRT for prostate cancers.

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  • 日本放射線技術學會雜誌

    日本放射線技術學會雜誌 68(3), 290-298, 2012-03-20

    公益社団法人 日本放射線技術学会

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各種コード

  • NII論文ID(NAID)
    10030139363
  • NII書誌ID(NCID)
    AN00197784
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    03694305
  • NDL 記事登録ID
    023640176
  • NDL 請求記号
    Z19-205
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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