Clinical relation between BPPV and osteoporosis

  • Yamanaka Toshiaki
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine
  • Shirota Shiho
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine
  • Sawai Yachiyo
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine
  • Murai Takayuki
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine
  • Shimizu Naoki
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine
  • Fukuda Takehiko
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine
  • Okamoto Hideyuki
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine
  • Fujita Nobuya
    Department of Otorhinolaryngology, Nara Prefectural Nara Hospital
  • Hosoi Hiroshi
    Department of Otolaryngology-Head and Neck Surgery, Nara Medical University School of Medicine

Bibliographic Information

Other Title
  • BPPVと骨粗鬆症の臨床的関係

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Abstract

This study was designed to investigate bone mineral density in patients with idiopathic BPPV to determine whether there is a clinical association between etiologically unknown (idiopathic) BPPV and osteoporosis. Dual energy X-ray absorptiometry was used to measure the bone mineral density (BMD) at lumbar vertebrae L2L4 in menopausal women over the age of 50 years who had been diagnosed as having idiopathic BPPV. A BMD value of less than 70% of the young adult mean (YAM) was regarded as indicating the presence of osteoporosis. The overall prevalence of osteoporosis in patients with BPPV was 27.5%, which was almost the same as that in a previously reported national survey. However, the rate of concurrent osteoporosis was higher among patients with recurrent BPPV (38.9%) than among those with non-recurrent BPPV (21.2%). Subjects with recurrent BPPV had a lower BMD (72.4% of the YAM) than those with non-recurrent BPPV. Subjects with multiple occurrences had an even lower BMD (69.4% of the YAM) and were classified as having osteoporosis. Thus, BPPV and osteoporosis may have similar pathogenetic mechanisms associated with calcium metabolism in both otoconia and bone. These results suggest that idiopathic BPPV with osteoporosis may be capable of recurring.

Journal

  • Equilibrium Research

    Equilibrium Research 71 (1), 33-39, 2012

    Japan Society for Equilibrium Research

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