Improvement of Temperature-responsive Drug Release from Collagen-mimic Dendrimers

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著者

    • KOJIMA Chie
    • Nanoscience and Nanotechnology Research Center, Osaka Prefecture University
    • SUEHIRO Tomoyuki
    • Nanoscience and Nanotechnology Research Center, Osaka Prefecture University

抄録

Gelatin, a thermally denatured collagen, forms a temperature-dependent gel, in which the efficiency of the collagen-like triple helix is dependent on temperature. In this study, (proline–hydroxyproline–glycine)<i><sub>n</sub></i> peptides were modified at the dendrimer to produce a type of collagen-mimic dendrimer. These dendrimers worked as a drug carrier with thermosensitive release capabilities and could retain rose bengal molecules stably.

収録刊行物

  • Chemistry letters

    Chemistry letters 40(11), 1249-1251, 2011-11-05

    公益社団法人 日本化学会

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各種コード

  • NII論文ID(NAID)
    10030220025
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    03667022
  • データ提供元
    CJP書誌  J-STAGE 
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