Liver transplantation for patients with human immunodeficiency virus and hepatitis C virus coinfection with special reference to hemophiliac recipients in Japan.

• Eguchi, Susumu

• Soyama, Akihiko

• Hidaka, Masaaki

• Takatsuki, Mitsuhisa

• Muraoka, Izumi

• Tomonaga, Tetsuo

• Kanematsu, Takashi

抄録

Liver transplantation for patients with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) remains challenging. The advent of highly active antiretroviral therapy (HAART) for HIV has reduced mortality from opportunistic infection related to acquired immunodeficiency syndrome dramatically, while about 50% of patients die of end-stage liver cirrhosis resulting from HCV. In Japan, liver cirrhosis frequently develops after HCV-HIV coinfection resulting from previously transfused infected blood products for hemophilia. The problems of liver transplantation for those patients arise from the need to control calcineurin inhibitor with HAART drugs, the difficulty of using interferon after liver transplantation with HAART, and the need to control intraoperative coagulopathy associated with hemophilia. We review published reports of liver transplantation for these patients in the updated world literature.

Surgery Today, 41(10), pp.1325-1331; 2011

収録刊行物

• Surgery Today

  Surgery Today 41 (10), 1325-1331, 2011-10

  Springer Verlag

キーワード

• Coinfection
• Hepatitis C virus
• Highly active antiretroviral therapy
• Human immunodeficiency virus
• Liver transplantation

詳細情報

• CRID: 1050850247228246784
• NII論文ID: 10030228509
• NII書誌ID: AA10824685
• ISSN: 09411291
• ISSN: 14362813
• HANDLE: 10069/26865
• Web Site: https://nagasaki-u.repo.nii.ac.jp/records/12695
• Web Site: https://search.jamas.or.jp/link/ui/2012198328
• 本文言語コード: en
• 資料種別: journal article
• データソース種別:
  • IRDB
  • CiNii Articles