16S ribosomal RNA 遺伝子を用いた歯周病患者の唾液中細菌叢の網羅的検出 Comprehensive detection of bacterial flora in saliva of patients with periodontal disease using 16S ribosomal RNA gene

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著者

    • 佐野 直人 SANO Naoto
    • 佐賀大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Saga University
    • 山下 佳雄 YAMASHITA Yoshio
    • 佐賀大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Saga University
    • 後藤 昌昭 GOTO Masaaki
    • 佐賀大学医学部歯科口腔外科学講座 Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Saga University

抄録

More than 700 bacterial species, of which over 50% have not been cultivated, have been detected in the oral cavity. Although research on organisms of caries or periodontosis is progressing, there are very few reports on studies of normal flora in the mouth. Therefore, we identified saliva flora including those that cannot be cultivated, using 16S ribosomal RNA gene which it has only bacteria.<br>We used this method to analyze bacterial flora in saliva of patients with periodontal disease, and compared the results with healthy subjects. Consequently, bacterias such as <i>Peptostreptococcus</i>, <i>Veillonella</i>, <i>Clostridium</i>, <i>porphyromonas</i>, <i>Capnocytophaga</i> were detected, which are normally not seen in healthy subjects. This method could help clarify the symptoms of periodontal disease or odontogenic infection.

収録刊行物

  • 日本口腔科学会雜誌

    日本口腔科学会雜誌 60(3), 219-225, 2011-07-10

    特定非営利活動法人 日本口腔科学会

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各種コード

  • NII論文ID(NAID)
    10030270876
  • NII書誌ID(NCID)
    AN00189050
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    00290297
  • NDL 記事登録ID
    11217749
  • NDL 雑誌分類
    ZS43(科学技術--医学--耳鼻咽喉科学) // ZS44(科学技術--医学--歯科学・口腔外科学)
  • NDL 請求記号
    Z19-215
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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