5-FU, ビタミンA, 放射線併用療法を行った腺様嚢胞癌の1例 A case of adenoid cystic carcinoma treated with concurrent combination therapy with 5-Fluorouracil, vitamin A, and radiation (FAR therapy)

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著者

    • 石井 広太郎 ISHII Kotaro
    • 九州大学大学院歯学研究院口腔顎顔面病態学講座・顎顔面口腔外科学分野 Department of Oral and Maxillofacial Surgery, Graduate School of Dental Science, Kyushu University
    • 窪田 泰孝 KUBOTA Yasutaka
    • 九州大学大学院歯学研究院口腔顎顔面病態学講座・顎顔面口腔外科学分野 Department of Oral and Maxillofacial Surgery, Graduate School of Dental Science, Kyushu University
    • 松浦 理城 [他] MATSUURA Satoshi
    • 九州大学大学院歯学研究院口腔顎顔面病態学講座・顎顔面口腔外科学分野 Department of Oral and Maxillofacial Surgery, Graduate School of Dental Science, Kyushu University
    • 清水 真弓 SHIMIZU Mayumi
    • 九州大学大学院歯学研究院口腔顎顔面病態学講座・口腔画像情報科学分野 Department of Oral Radiology, Graduate School of Dental Science, Kyushu University
    • 小林 家吉 KOBAYASHI Ieyoshi
    • 九州大学大学院歯学研究院口腔顎顔面病態学講座・口腔病理学研究分野 Department of Oral Pathology, Graduate School of Dental Science, Kyushu University
    • 白砂 兼光 SHIRASUNA Kanemitsu
    • 九州大学大学院歯学研究院口腔顎顔面病態学講座・顎顔面口腔外科学分野 Department of Oral and Maxillofacial Surgery, Graduate School of Dental Science, Kyushu University

抄録

This report presents a case of adenoid cystic carcinoma (ACC), treated with concurrent combination therapy with 5-Fluorouracil, vitamin A, and radiation (FAR therapy). The case was a 61-year-old male with ACC of the left mandible and lung metastasis (T4N0M1). The tumor extended into the mandibular ramus and the pterygo-mandibular and parotid spaces with severe bone destruction. The patient underwent FAR treatment, resulting in a decrease in size of the primary tumor (56% reduction) and in an increase in formation of bone-like tissue. Successful pain control was acquired. However, the unirradiated metastatic lung lesions continued to progress and a metastatic brain lesion eventually appeared. The patient died 19 months after the initial presentation. This case suggests that FAR treatment is effective for improving the quality of life of patients with inoperable ACC.

収録刊行物

  • 日本口腔科学会雜誌

    日本口腔科学会雜誌 60(3), 254-258, 2011-07-10

    特定非営利活動法人 日本口腔科学会

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各種コード

  • NII論文ID(NAID)
    10030270988
  • NII書誌ID(NCID)
    AN00189050
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    00290297
  • NDL 記事登録ID
    11217875
  • NDL 雑誌分類
    ZS43(科学技術--医学--耳鼻咽喉科学) // ZS44(科学技術--医学--歯科学・口腔外科学)
  • NDL 請求記号
    Z19-215
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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