アルコール性肝硬変患者に生じた舌対称性脂肪腫症の1例 Symmetric lipomatosis of the tongue arising in a patient with alcoholic liver cirrhosis

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著者

    • 五十嵐 友樹 IKARASHI Yuki
    • 新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野 Division of Oral and maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Sciences
    • 飯田 明彦 IIDA Akihiko
    • 新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野 Division of Oral and maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Sciences
    • 小林 孝憲 [他] KOBAYASHI Takanori
    • 新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野 Division of Oral and maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Sciences
    • 朔 敬 SAKU Takashi
    • 新潟大学大学院医歯学総合研究科口腔病理学分野 Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences
    • 林 孝文 HAYASHI Takafumi
    • 新潟大学大学院医歯学総合研究科顎顔面放射線学分野 Division of Oral and maxillofacial Radiology, Niigata University Graduate School of Medical and Dental Sciences
    • 高木 律男 TAKAGI Ritsuo
    • 新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野 Division of Oral and maxillofacial Surgery, Niigata University Graduate School of Medical and Dental Sciences

抄録

Symmetric lipomatosis of the tongue (SLT) is a rare condition related to generalized lipidosis, often caused by chronic alcoholism. It is characterized by multiple lipomatous nodules symmetrically located within the tongue. We report a case of SLT arising in a 62-year-old man with a long history of alcoholic liver cirrhosis. He had multiple soft nodular protrusions on the left margin of the tongue for months, caused by involuntary self-inflicted tongue bites. Although computed tomography showed fatty masses on both sides of the tongue, no elevated tumor mass existed on the right margin. To prevent further tongue biting, the nodules were surgically removed. Histopathologically, the nodules consisted of mature adipose tissue lobules, which were clearly demarcated from the surrounding muscle tissue. Because of the patient's lipidosis and unusual presentation of multiple lesions, the lesion was finally diagnosed to be SLT. A literature review showed 27 documented cases of SLT, mostly in Asian elderly men, and 73 % of all cases were associated with liver failure. SLT can be regarded as reactive hyperplasia of adipocytes in granulation tissue as a response to traumatic stimuli rather than neoplasia. Surgical intervention may be considered when the tongue lesions are traumatic and when perioperative management is indicated.

Symmetric lipomatosis of the tongue (SLT) is a rare condition related to generalized lipidosis, often caused by chronic alcoholism. It is characterized by multiple lipomatous nodules symmetrically located within the tongue. We report a case of SLT arising in a 62-year-old man with a long history of alcoholic liver cirrhosis. He had multiple soft nodular protrusions on the left margin of the tongue for months, caused by involuntary self-inflicted tongue bites. Although computed tomography showed fatty masses on both sides of the tongue, no elevated tumor mass existed on the right margin. To prevent further tongue biting, the nodules were surgically removed. Histopathologically, the nodules consisted of mature adipose tissue lobules, which were clearly demarcated from the surrounding muscle tissue. Because of the patient's lipidosis and unusual presentation of multiple lesions, the lesion was finally diagnosed to be SLT. A literature review showed 27 documented cases of SLT, mostly in Asian elderly men, and 73 % of all cases were associated with liver failure. SLT can be regarded as reactive hyperplasia of adipocytes in granulation tissue as a response to traumatic stimuli rather than neoplasia. Surgical intervention may be considered when the tongue lesions are traumatic and when perioperative management is indicated.

収録刊行物

  • 日本口腔外科学会雑誌

    日本口腔外科学会雑誌 57(3), 119-123, 2011-03-20

    社団法人 日本口腔外科学会

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各種コード

  • NII論文ID(NAID)
    10030271637
  • NII書誌ID(NCID)
    AN00189163
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00215163
  • NDL 記事登録ID
    11052074
  • NDL 雑誌分類
    ZS44(科学技術--医学--歯科学・口腔外科学)
  • NDL 請求記号
    Z19-145
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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