Application of polyglycolic acid sheet and fibrin glue spray for partial glossectomy: Comparison with artificial dermis

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  • TAKEUCHI Junichiro
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine
  • UMEDA Masahiro
    Department of Oral and Maxillofacial Surgery, Nagasaki University Graduate School of Biomedical Sciences
  • MURATA Maho
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine
  • KAKEI Yasumasa
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine
  • KIMOTO Akira
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine
  • SUZUKI Hiroaki
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine
  • SHIGETA Takashi
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine
  • RI Shinsho
    Department of Oral and Maxillofacial Surgery, Shinko Kakogawa Hospital
  • KOMORI Takahide
    Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine

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Other Title
  • 舌部分切除術におけるポリグリコール酸シートおよびフィブリン糊スプレーの使用経験 —コラーゲン使用人工皮膚との比較—
  • 舌部分切除術におけるポリグリコール酸シートおよびフィブリン糊スプレーの使用経験--コラーゲン使用人工皮膚との比較
  • シタブ ブン セツジョジュツ ニ オケル ポリグリコールサン シート オヨビ フィブリンノリ スプレー ノ シヨウ ケイケン コラーゲン シヨウ ジンコウ ヒフ ト ノ ヒカク
  • Application of polyglycolic acid sheet and fibrin glue spray for partial glossectomy: comparison with artificial dermis (in Japanese)

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Abstract

Various biomaterials, as well as autologous mucosal or skin grafts, have been applied to open wounds after partial glossectomy. We clinically evaluated postoperative pain and scar contracture in 37 patients who underwent partial glossectomy followed by covering with a polyglycolic acid （PGA） sheet and fibrin glue spray, as compared with 31 patients in whom an artificial dermis was used.<br> NSAIDs were administered for an average of 7.2 days postoperatively in the artificial dermis group and 5.9 days in the PGA sheet group. Scar contracture in patients with tongue cancer was milder in the PGA sheet group than in the artificial dermis group, although those with intraepithelial lesions showed minimal scar contracture in both groups.<br> These findings showed that the application of a PGA sheet and fibrin glue for open wounds of partial glossectomy was useful for promoting early oral feeding, rapid relief from postoperative pain, and prevention of scar contracture.

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