Isolated extramedullary relapse of acute lymphocytic leukemia in the maxilla after allogeneic stem cell transplantation

• WADA Keinoshin

  Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University Department of Oral and Maxillofacial Surgery, Biwako Ohashi Hospital

• OHBAYASHI Yumiko

  Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University

• IWASAKI Akinori

  Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University

• OGAWA Takaaki

  Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University

• MIYAKE Minoru

  Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University

• MATSUI Yoshiro

  Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University

Bibliographic Information

Other Title

• 造血幹細胞移植後に上顎へ髄外再発した急性リンパ性白血病の1例
• ゾウケツ カン サイボウ イショク ゴ ニ ウワアゴ エ ズイガイ サイハツ シタ キュウセイ リンパセイ ハッケツビョウ ノ 1レイ

Abstract

We report a case of extramedullary relapse of acute lymphocytic leukemia （ALL） in the maxilla of 22-year-old man after an allogeneic stem cell transplantation. Relapse of ALL usually occurs in either the central nerve system or a testis because these organs are independent of systemic immunity. A complete remission had been achieved temporarily by both induction chemotherapy and stem cell transplantation. One year after transplantation, a relapse occurred with an extramedullary mass in the right side of the maxilla. The patient received chemotherapy and local radiation therapy of the mass because the bone marrow was not involved. Bone marrow relapse occurred about 6 months after the extramedullary relapse. Unfortunately, the patient died of sepsis during re-induction therapy. This case is the first domestic report of an isolated extramedullary relapse of ALL in the maxilla after allogeneic stem cell transplantation.

Journal

• Japanese Journal of Oral and Maxillofacial Surgery

  Japanese Journal of Oral and Maxillofacial Surgery 57 (12), 675-679, 2011

  Japanese Society of Oral and Maxillofacial Surgeons

Keywords

• acute lymphocytic leukemia
• allogeneic stem cell transplantation
• maxilla
• extramedullary relapse
• T-ALL/LBL

Details

• CRID: 1390001206532464768
• NII Article ID: 130004685719
• NII Article ID: 10030273266
• NII Book ID: AN00189163
• DOI: 10.5794/jjoms.57.675
• ISSN: 21861579
• ISSN: 00215163
• NDL BIB ID: 023420147
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I023420147
• Web Site: https://search.jamas.or.jp/link/ui/2012118166
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed