Promising Application of Dynamic Nuclear Polarization for in Vivo ^<13>C MR Imaging

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著者

    • YEN Yi-Fen
    • Global Applied Science Laboratory, GE Healthcare, Menlo Park
    • NAGASAWA Kiyoshi
    • Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata
    • NAKADA Tsutomu
    • Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata

抄録

Use of hyperpolarized <sup>13</sup>C in magnetic resonance (MR) imaging is a new technique that enhances signal tens of thousands-fold. Recent <i>in vivo</i> animal studies of metabolic imaging that used hyperpolarized <sup>13</sup>C demonstrated its potential in many applications for disease indication, metabolic profiling, and treatment monitoring. We review the basic physics for dynamic nuclear polarization (DNP) and <i>in vivo</i> studies reported in prostate cancer research, hepatocellular carcinoma research, diabetes and cardiac applications, brain metabolism, and treatment response as well as investigations of various DNP <sup>13</sup>C substrates.<br>

収録刊行物

  • Magnetic resonance in medical sciences : MRMS

    Magnetic resonance in medical sciences : MRMS 10(4), 211-217, 2011-12-01

    日本磁気共鳴医学会

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各種コード

  • NII論文ID(NAID)
    10030284525
  • NII書誌ID(NCID)
    AA11648770
  • 本文言語コード
    ENG
  • 資料種別
    REV
  • ISSN
    13473182
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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