Diffusion-weighted Imaging with Relative Signal Intensity Statistical Thresholding for Delineating Prostate Cancer Tumors

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著者

    • YAMAZOE Shinji
    • Department of Radiology, Jikei University School of Medicine, Kashiwa Hospital
    • TAKAHARA Taro
    • Department of Biomedical Engineering, Tokai University School of Engineering
    • SHIMIZU Kanichiro
    • Department of Radiology, Jikei University School of Medicine, Kashiwa Hospital
    • OUCHI Kotaro
    • Department of Radiology, Jikei University School of Medicine, Kashiwa Hospital
    • MOGAMI Takuji
    • Department of Radiology, Jikei University School of Medicine, Kashiwa Hospital
    • HARADA Junta
    • Department of Radiology, Jikei University School of Medicine, Kashiwa Hospital

抄録

Purpose: We assessed the utility of diffusion-weighted imaging (DWI) with relative signal intensity (rSI) statistical thresholding for delineating prostate cancer tumors.<br> Materials and Methods: Seventeen patients with prostate cancer underwent DWI before total prostatectomy. We measured standard deviation (SD) of the signal intensity (SI) of the lesser pelvic space at DWI, created rSI maps, displaying signal intensities with SDs of only >+3, >+3.5, >+4, or >+5, and assessed correlation between the proportion of cancerous area on the 4 different rSI maps and that on pathological slices.<br> Results: We could detect prostate cancer on rSI maps for all cases with SD >+3, but not 2 cases with SD >+3.5, five with SD >+4, and eight with SD >+5. The correlation coefficients (R) between the proportion of cancerous area on pathological examination and rSI maps were 0.7464 for SD >+3 (<i>P</i>=0.0006); 0.6469 for SD >+3.5 (<i>P</i>=0.0050); 0.6459 for SD >+4 (<i>P</i>=0.0051), and 0.4540 for SD >+5 (<i>P</i>=0.0671).<br> Conclusion: DWI-based rSI mapping may be used to delineate the extent of prostate cancer. We achieved best correlation between ratio of cancerous area of the lesser pelvic space on pathological examination and on rSI map using a threshold with SD >+3 of the SI.<br>

収録刊行物

  • Magnetic resonance in medical sciences : MRMS

    Magnetic resonance in medical sciences : MRMS 11(1), 1-8, 2012-03-01

    日本磁気共鳴医学会

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各種コード

  • NII論文ID(NAID)
    10030284712
  • NII書誌ID(NCID)
    AA11648770
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13473182
  • データ提供元
    CJP書誌  J-STAGE 
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