Three Cases of Renal Cell Carcinoma Metastasizing to the Head and Neck

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  • Ito Rie
    Yao Municipal Hospital
  • Nishiike Suetaka
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine
  • Tomiyama Yoichiro
    Sakai Municipal Hospital
  • Yoshii Tadashi
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine
  • Yamamoto Yoshifumi
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine
  • Inohara Hidenori
    Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine

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Other Title
  • 頭頸部領域に転移を来した腎細胞癌の３例
  • 症例報告 頭頸部領域に転移を来した腎細胞癌の3例
  • ショウレイ ホウコク アタマ ケイブ リョウイキ ニ テンイ オ キタシタ ジンサイボウガン ノ 3レイ

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Abstract

Renal cell carcinoma (RCC) tends to metastasize hematogenously, although metastasis to the head and neck is rare. We report 3 cases of RCC head and neck metastasis within the last 6 years. Case 1: A 74-year-old woman presented with cervical metastasis from RCC 4 years after right total nephrectomy, involving modified neck dissection. She later had additional surgery and radiation for further distant metastases, survived almost 5 years after the first neck metastasis. Case 2: A 60-year-old man showed metastatic RCC in the right parotid gland 3 years after right total nephrectomy, involving superficial parotidectomy. Case 3: A 54-year-old man presented with a metastasis lesion from RCC to the right maxillary sinus 7 years after left total nephrectomy, involving total maxillectomy. Distant metastasis reportedly often occurs long after initial primary RCC treatment. Physicians considering metastatic RCC in differential head and neck diagnosis and resection could conceivably promote better prognosis.

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