Ingenuity and usefulness of the preliminary tablet-based regimens for bowel cleansing prior to colonoscopy - Randomized comparative study regarding patient acceptability and cleansing effect-

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  • 錠剤型経口腸管洗浄剤を用いた大腸内視鏡前処置法の工夫と有用性─患者受容性および腸管洗浄効果に関する無作為比較試験─
  • 錠剤型経口腸管洗浄剤を用いた大腸内視鏡前処置法の工夫と有用性 : 患者受容性および腸管洗浄効果に関する無作為比較試験
  • ジョウザイガタ ケイコウ チョウカン センジョウザイ オ モチイタ ダイチョウ ナイシキョウ マエショチホウ ノ クフウ ト ユウヨウセイ : カンジャ ジュヨウセイ オヨビ チョウカン センジョウ コウカ ニ カンスル ムサクイ ヒカク シケン

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Abstract

Polyethylene glycol (PEG) is used in colonoscopy as a preliminary treatment, but the effects of its taste, smell, and dose on patients are unpleasant. In this study, in order to reveal whether the amount of medication can be reduced in the same manner as sodium phosphate tablets (Group A), we performed a prospective test comparing half-dose administrations of PEG (Group B) and magnesium citrate (Group C). As a result, it was revealed that patient acceptability evaluations were significantly superior in Group A compared to those of Group B. Moreover, Group A was observed to have significantly higher acceptability compared to the other groups when comparing ease in taking agents for bowel-cleanser in patients undergoing colonoscopy. On the other hand, in the evaluation of the bowel cleansing effect, a good bowel cleansing effect was observed in approximately 90% of patients in all administration groups, with no significant differences observed among the 3 Groups.<BR>From the above, it was considered that administering half of the specified dosage with the concomitant use of food for colonoscopy and laxatives may improve patients’ acceptance of sodium phosphate tablet by maintaining the cleansing effect.

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