Evaluation of the NOW Malaria Immunochromatographic Test for Quantitative Diagnosis of Falciparum and Vivax Malaria Parasite Density

Access this Article

Search this Article

Author(s)

    • KATAKAI Yuko
    • Department of Tropical Medicine and Malaria, Research Institute, National Center for Global Health and Medicine
    • KOMAKI YASUDA Kanako
    • Department of Tropical Medicine and Malaria, Research Institute, National Center for Global Health and Medicine
    • KANO Shigeyuki
    • Department of Tropical Medicine and Malaria, Research Institute, National Center for Global Health and Medicine

Abstract

The NOW<sup>®</sup> Malaria Test, an immunochromatographic test (ICT), was evaluated to determine its ability to quantitatively detect malaria parasites using 100 blood samples from Thailand, including 50 <i>Plasmodium falciparum</i> (Pf) infections and 50 <i>P. vivax</i> (Pv) infections. Intensities of the thickness of the visible bands of the positive ICT were compared with the parasite densities. In cases of Pf infection, the intensities of both HRP-2 bands (T1 bands: Pf specific bands) and aldolase bands (T2 bands: pan-<i>Plasmodium</i> bands) correlated with the parasite densities. The intensities of T2 bands in Pf positive samples showed better correlation with the parasite densities than the T1 bands. In the cases of Pv infection, the intensities of T2 bands were also well correlated with parasite density. These results suggest that the ICT is useful not only for rapid detection of malaria parasites but also for estimating parasite density.

Journal

  • Tropical Medicine and Health

    Tropical Medicine and Health 39(4), 105-108, 2011-12-01

    Japanese Society of Tropical Medicine

Codes

  • NII Article ID (NAID)
    10030394640
  • NII NACSIS-CAT ID (NCID)
    AA11912846
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    13488945
  • Data Source
    CJP  J-STAGE 
Page Top