Molecular characterization of adult T-cell leukemia/lymphoma (ATLL) cells

• NAKAMURA Motonobu

  <i>Department of Dermatology, University of Occupational and Environmental Health</i>

Bibliographic Information

Other Title

• ATLLの分子学的特性

Abstract

Adult T-cell leukemia/lymphoma (ATLL) is a peripheral CD4⁺ CD25⁺ T-cell malignancy caused by human T-cell leukemia/lymphoma virus type I (HTLV-I). The ATLL cells frequently infiltrate into the epidermis and form a Pautrier's microabscess. The expression of CCR4 and its ligands TARC/CCL17 and MDC/CCL22 by ATLL cells may underlie the epidermotropism and microabscess formation.[Skin Cancer (Japan) 2009 ; 24 : 206-211]

Journal

• Skin Cancer

  Skin Cancer 24 (2), 206-211, 2009

  The Japanese Skin Cancer Society

Keywords

• Adult T-cell leukemia/lymphoma
• ATLL
• MDC/CCL22
• TARC/CCL17
• CCR4

Details

• CRID: 1390282679312133120
• NII Article ID: 10030441186
• NII Book ID: AN10087647
• DOI: 10.5227/skincancer.24.206
• ISSN: 18843549
• ISSN: 09153535
• Web Site: https://search.jamas.or.jp/link/ui/2010018845
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed