Insight into the Functional Conversion of Respiratory Enzymes from the Crystallographic Studies of Nitric Oxide Reductases

• HINO Tomoya

  Department of Biotechnology, Graduate School of Engineering, Tottori University

• TOSHA Takehiko

  RIKEN SPring-8 Center

• SHIRO Yoshitsugu

  RIKEN SPring-8 Center

Bibliographic Information

Other Title

• 一酸化窒素還元酵素の結晶構造から見えてきた呼吸酵素の機能変換
• イッサンカ チッソ カンゲン コウソ ノ ケッショウ コウゾウ カラ ミエテ キタ コキュウ コウソ ノ キノウ ヘンカン

Abstract

Nitric oxide reductase (NOR) is a transmembrane enzyme that catalyzes reductive coupling of two molecules of nitric oxide NO to form nitrous oxide N₂O in microbial denitrification process. Recently, we solved the crystal structures of two types of bacterial NORs, cNOR and qNOR. As has been proposed, their overall structures are similar to those of aerobic and microaerobic respiratory enzymes, cytochrome c oxidases, supporting the idea that NORs are classified as the divergent members of respiratory Heme-Cupper oxidase superfamily. By comparing these structural data in detail, we can briefly describe functional conversion of the respiratory enzyme in their molecular evolution.<br>

Journal

• Seibutsu Butsuri

  Seibutsu Butsuri 52 (4), 186-189, 2012

  The Biophysical Society of Japan General Incorporated Association

Keywords

• Nitric oxide
• Nitrous oxide
• NO reductase
• Denitrification
• Respiratory enzymes
• X-ray crystallography

Details

• CRID: 1390282681510927488
• NII Article ID: 10030494649
• NII Book ID: AN00129693
• DOI: 10.2142/biophys.52.186
• COI: 1:CAS:528:DC%2BC38XhtFOrt7jF
• ISSN: 13474219
• ISSN: 05824052
• NDL BIB ID: 023910289
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I023910289
• Web Site: https://www.jstage.jst.go.jp/article/biophys/52/4/52_186/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2012332606
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed