A study on the sealing ability and antibacterial activity of Ca_3SiO_5/CaCl_2 composite cement for dental applications

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Author(s)

    • WANG Xiaohong
    • Department of Endodontics, Stomatological College, TongJi University
    • CHANG Jiang
    • Biomaterials & Tissue Engineering Research Center, Shanghai Institute of Ceramics, Chinese Academy of Sciences
    • HU Sheng
    • Biomaterials & Tissue Engineering Research Center, Shanghai Institute of Ceramics, Chinese Academy of Sciences

Abstract

The objective of this study was to evaluate the sealing ability and antibacterial activity of Ca<sub>3</sub>SiO<sub>5</sub>/CaCl<sub>2</sub> composite cement. Fifty maxillary anterior teeth were instrumented according to step-back technique and filled with experimental and control materials. Toevaluate the sealing ability, a fluid transport model using glucose was employed for quantitative analysis of endodontic microleakage. To evaluate antibacterial activity, <i>E. colias</i> (ATCC 25922) was cultivated on agar plates. Results showed that the sealing ability of Ca<sub>3</sub>SiO<sub>5</sub>/CaCl<sub>2</sub> composite cement and cortisomol paste were higher than that of zinc oxide-eugenol (ZOE) cement, and that nosignificant difference was observed between Ca<sub>3</sub>SiO<sub>5</sub>/CaCl<sub>2</sub> composite cement and cortisomol paste. On antibacterial activity, Ca<sub>3</sub>SiO<sub>5</sub>/CaCl<sub>2</sub> composite cements composed of varying amounts of CaCl<sub>2</sub> (0-15%) exhibited similar levels of activity against <i>E. colias</i>as calcium hydroxide cement, whereas cortisomol paste had little effect on <i>E. colias</i>. All these results suggested that Ca<sub>3</sub>SiO<sub>5</sub>/CaCl<sub>2</sub> composite cement demonstrated good potential for root canal treatment applications.

Journal

  • Dental Materials Journal

    Dental Materials Journal 31(4), 617-622, 2012-07-01

    The Japanese Society for Dental Materials and Devices

References:  26

Codes

  • NII Article ID (NAID)
    10030501712
  • NII NACSIS-CAT ID (NCID)
    AA10443149
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    02874547
  • Data Source
    CJP  J-STAGE 
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