天然物由来のマイコトキシン生産阻害物質

• 作田 庄平

  東京大学大学院農学生命科学研究科

書誌事項

タイトル別名

• Mycotoxin production ihbitors from natural products
• Mycotoxin production inhibitors from natural products

抄録

  Mycotoxin production inhibitors are useful as lead compounds in the development of effective drugs for preventing mycotoxin contamination in food and feed. These inhibitors also serve as valuable probes for investigating the regulatory mechanisms that control mycotoxin production in fungi. We screened microbial metabolites and essential oils to find inhibitors that specifically targeted aflatoxin production in Aspergillus parasiticus and trichothecene production in Fusarium graminearum. This led to findings of aflatoxin production inhibitory activity of aflastatins, blasticidins A and S, dioctatin A, dillapiol, apiol and spiroethers. We also found trichothecene production inhibitory activity of spiroethers, precocenes and piperitone. Our work on these compounds is reviewed.

収録刊行物

• マイコトキシン

  マイコトキシン 60 (2), 79-86, 2010

  日本マイコトキシン学会

キーワード

• アフラトキシン，
• デオキシニバレノール
• アフラスタチン
• ブラストサイジン
• ジオクタチン
• プレコセン

詳細情報

• CRID: 1390282679761765632
• NII論文ID: 10030541115
• NII書誌ID: AN00334513
• DOI: 10.2520/myco.60.79
• COI: 1:CAS:528:DC%2BC3cXhsVOrtb7J
• ISSN: 18810128
• ISSN: 02851466
• Web Site: https://agriknowledge.affrc.go.jp/RN/2010793433
• Web Site: https://search.jamas.or.jp/link/ui/2011303709
• 本文言語コード: en
• データソース種別:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可