Correlation-Based Image Reconstruction Methods for Magnetic Particle Imaging

• ISHIHARA Yasutoshi

  Meiji University

• KUWABARA Tsuyoshi

  Mobil Techno Corporation

• HONMA Takumi

  Meiji University

• NAKAGAWA Yohei

  Meiji University

抄録

Magnetic particle imaging (MPI), in which the nonlinear interaction between internally administered magnetic nanoparticles (MNPs) and electromagnetic waves irradiated from outside of the body is utilized, has attracted attention for its potential to achieve early diagnosis of diseases such as cancer. In MPI, the local magnetic field distribution is scanned, and the magnetization signal from MNPs within a selected region is detected. However, the signal sensitivity and image resolution are degraded by interference from magnetization signals generated by MNPs outside of the selected region, mainly because of imperfections (limited gradients) in the local magnetic field distribution. Here, we propose new methods based on correlation information between the observed signal and the system function—defined as the interaction between the magnetic field distribution and the magnetizing properties of MNPs. We performed numerical analyses and found that, although the images were somewhat blurred, image artifacts could be significantly reduced and accurate images could be reconstructed without the inverse-matrix operation used in conventional image reconstruction methods.

収録刊行物

• IEICE Transactions on Information and Systems

  IEICE Transactions on Information and Systems E95-D (3), 872-879, 2012

  一般社団法人 電子情報通信学会

キーワード

• magnetic particle imaging
• MPI
• molecular imaging
• image reconstruction
• correlation
• nanoparticles

詳細情報

• CRID: 1390282679355159936
• NII論文ID: 10030611855
• NII書誌ID: AA10826272
• DOI: 10.1587/transinf.e95.d.872
• BIBCODE: 2012IEITI..95..872I
• ISSN: 17451361
• ISSN: 09168532
• Web Site: http://www.jstage.jst.go.jp/article/transinf/E95.D/3/E95.D_3_872/_pdf
• 本文言語コード: en
• データソース種別:
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• 抄録ライセンスフラグ: 使用不可