Xanthogranuloma of the Sellar Region -Case Report-

  • ARAI Atsushi
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • NISHIHARA Masamitsu
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • SASAYAMA Takashi
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • AIHARA Hideo
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • HOSODA Kohkichi
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • ITOH Tomoo
    Department of Pathology, Kobe University Graduate School of Medicine
  • SAKAGAMI Yoshio
    Department of Neurosurgery, Hyogo Prefectural Awaji Hospital
  • KUWAMURA Keiichi
    Department of Neurosurgery, Hyogo Prefectural Awaji Hospital
  • KOHMURA Eiji
    Department of Neurosurgery, Kobe University Graduate School of Medicine

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  • —Case Report—

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Abstract

A 55-year-old woman presented with a rare xanthogranuloma of the sellar region after complaining of severe headache and visual disturbance 3 months previously. Clinical examination showed she was alert with early signs of bitemporal hemianopsia. Endocrinological examination revealed hypopituitarism. Magnetic resonance imaging showed an intrasellar mass extending into the suprasellar region and compressing the optic chiasma, which appeared homogeneously hyperintense on T1-weighted images. Endonasal transsphenoidal resection of the tumor was performed. Histological examination disclosed granulomatous tissue with cholesterol clefts, hemosiderin deposits, fibrous tissues, and macrophages containing rich fat. The histological diagnosis was xanthogranuloma of the sellar region. Her visual symptoms recovered postoperatively although the hypopituitarism remained. Xanthogranuloma of the sellar region is rare, but must be considered in the differential diagnosis of tumors of the sellar region.<br>

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