Stereoselective Synthesis of a Protected Form of (6R,7E,9S,10R,12Z)-6,9,10-Trihydroxy-7,12-hexadecadienoic Acid
The protected stereoisomer of a trihydroxy unsaturated fatty acid, which could be employed as a potential nigricanoside α-chain building block, was synthesized by using Evans asymmetric alkylation, Sharpless kinetic resolution, and diastereoselective reduction as the key steps.
- Bioscience, biotechnology, and biochemistry
Bioscience, biotechnology, and biochemistry 76(3), 605-607, 2012-03-23
Japan Society for Bioscience, Biotechnology, and Agrochemistry