Beneficial Effect of Hyperbaric Oxygen Therapy on the Follicular Survival in the Mouse Ovary after Transplantation

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著者

    • HAYASHI Satomi HAYASHI Satomi
    • Research Unit for Functional Genomics, National Research Center of Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine
    • ASANO Tomoyoshi ASANO Tomoyoshi
    • Research Unit for Functional Genomics, National Research Center of Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine
    • SUZUKI Hiroshi
    • Research Unit for Functional Genomics, National Research Center of Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine

抄録

A large proportion of follicles are lost during the initial ischemia that occurs after transplantation of ovarian tissues. Thus, the effect of hyperbaric oxygen therapy (HBO) on the follicular loss of ovarian tissues after transplantation was examined in mice. Ovarian slices from ICR mice were transplanted under the kidney capsule in ovariectomized ICR. Hyperbaric oxygen with 100% oxygen was initiated for 30 min at 2.5 atmospheres absolute immediately after transplantation, and this treatment was repeated at 48-h intervals for 2 weeks. The number of follicles was dramatically reduced at 2 weeks post transplantation. However, HBO was significantly effective in enhancing the survival of transplanted ovarian follicles. The survival rates of primordial and primary follicles in ovarian tissues of mice with HBO were significantly higher than those without HBO. These results indicate HBO can be effectively used for the enhancement of survival of transplanted ovarian tissues.

A large proportion of follicles are lost during the initial ischemia that occurs after transplantation of ovarian tissues. Thus, the effect of hyperbaric oxygen therapy (HBO) on the follicular loss of ovarian tissues after transplantation was examined in mice. Ovarian slices from ICR mice were transplanted under the kidney capsule in ovariectomized ICR. Hyperbaric oxygen with 100% oxygen was initiated for 30 min at 2.5 atmospheres absolute immediately after transplantation, and this treatment was repeated at 48-h intervals for 2 weeks. The number of follicles was dramatically reduced at 2 weeks post transplantation. However, HBO was significantly effective in enhancing the survival of transplanted ovarian follicles. The survival rates of primordial and primary follicles in ovarian tissues of mice with HBO were significantly higher than those without HBO. These results indicate HBO can be effectively used for the enhancement of survival of transplanted ovarian tissues.

収録刊行物

  • The Journal of reproduction and development

    The Journal of reproduction and development 58(2), 260-263, 2012-04-01

    日本繁殖生物学会

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各種コード

  • NII論文ID(NAID)
    10030754171
  • NII書誌ID(NCID)
    AA10936678
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    09168818
  • NDL 記事登録ID
    023602143
  • NDL 請求記号
    Z54-H305
  • データ提供元
    CJP書誌  NDL  IR  J-STAGE 
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