Beneficial Effect of Hyperbaric Oxygen Therapy on the Follicular Survival in the Mouse Ovary after Transplantation

• HAYASHI Satomi

  Research Unit for Functional Genomics, National Research Center of Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan

• ASANO Tomoyoshi

  Research Unit for Functional Genomics, National Research Center of Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan

• KAKIZAKI Ryujiro

  Research Unit for Functional Genomics, National Research Center of Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan

• SUZUKI Hiroshi

  Research Unit for Functional Genomics, National Research Center of Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan

Abstract

A large proportion of follicles are lost during the initial ischemia that occurs after transplantation of ovarian tissues. Thus, the effect of hyperbaric oxygen therapy (HBO) on the follicular loss of ovarian tissues after transplantation was examined in mice. Ovarian slices from ICR mice were transplanted under the kidney capsule in ovariectomized ICR. Hyperbaric oxygen with 100% oxygen was initiated for 30 min at 2.5 atmospheres absolute immediately after transplantation, and this treatment was repeated at 48-h intervals for 2 weeks. The number of follicles was dramatically reduced at 2 weeks post transplantation. However, HBO was significantly effective in enhancing the survival of transplanted ovarian follicles. The survival rates of primordial and primary follicles in ovarian tissues of mice with HBO were significantly higher than those without HBO. These results indicate HBO can be effectively used for the enhancement of survival of transplanted ovarian tissues.

Journal

• Journal of Reproduction and Development

  Journal of Reproduction and Development 58 (2), 260-263, 2012

  The Society for Reproduction and Development

Keywords

• Hyperbaric oxygen
• Mice
• Ovary
• Transplantation

Details

• CRID: 1390001206336115712
• NII Article ID: 10030754171
• NII Book ID: AA10936678
• DOI: 10.1262/jrd.11-133h
• COI: 1:STN:280:DC%2BC38zos1ClsQ%3D%3D
• ISSN: 13484400
• ISSN: 09168818
• NDL BIB ID: 023602143
• PubMed: 22156380
• Web Site: https://obihiro.repo.nii.ac.jp/records/897
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I023602143
• Web Site: https://www.jstage.jst.go.jp/article/jrd/58/2/58_11-133H/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2013185183
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed