Self-Reported Snoring Frequency and Incidence of Cardiovascular Disease: The Circulatory Risk in Communities Study (CIRCS)

• Nagayoshi Mako

  Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion

• Tanigawa Takeshi

  Department of Public Health, Doctoral Program in Social Medicine, Ehime University Graduate School of Medicine Department of Public Health, Doctoral Program in Social Medicine, Ehime University Graduate School of Medicine

• Yamagishi Kazumasa

  Osaka Medical Center for Health Science and Promotion Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba Osaka Medical Center for Health Science and Promotion Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba

• Sakurai Susumu

  Department of Public Health, Doctoral Program in Social Medicine, Ehime University Graduate School of Medicine Department of Public Health, Doctoral Program in Social Medicine, Ehime University Graduate School of Medicine

• Kitamura Akihiko

  Osaka Medical Center for Health Science and Promotion Osaka Medical Center for Health Science and Promotion

• Kiyama Masahiko

  Osaka Medical Center for Health Science and Promotion Osaka Medical Center for Health Science and Promotion

• Okada Takeo

  Osaka Medical Center for Health Science and Promotion Osaka Medical Center for Health Science and Promotion

• Maeda Kenji

  Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion

• Ohira Tetsuya

  Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion

• Imano Hironori

  Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Osaka Medical Center for Health Science and Promotion

• Sato Shinichi

  Chiba Prefectural Institute of Public Health Chiba Prefectural Institute of Public Health

• Iso Hiroyasu

  Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University Public Health, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University

• Cui Renzhe

• Ikeda Ai

• Noda Hiroyuki

• Ikehara Satoyo

• Muraki Isao

• Maruyama Kotatsu

• Sankai Tomoko

• Umesawa Mitsumasa

• Chei Choy-Lye

• Yokota Kimiko

• Tabata Minako

• Konishi Masamitsu

• Ishikawa Yoshinori

• Nakamura Masakazu

• Ido Masatoshi

• Shimamoto Takashi

• Iida Minoru

• Komachi Yoshio

• Saito Isao

• Hitsumoto Shinichi

• Yao Masayuki

抄録

Background: Although associations between snoring and cardiovascular disease have been reported in several prospective studies, there is limited evidence from Asian populations. The objective of this study was to determine if there is an association between self-reported snoring frequency and the incidence of cardiovascular disease in Japanese.<BR>Methods: The subjects were 2350 men and 4163 women aged 40 to 69 years who lived in 3 communities in Japan. All subjects were participants in the Circulatory Risk in Communities Study (CIRCS) and were followed for 6 years. Incidence of cardiovascular disease during the follow-up period comprised events of myocardial infarction, angina pectoris, sudden cardiac death and stroke.<BR>Results: During the 6-year follow-up period, 97 participants (56 men and 41 women) had cardiovascular events. After adjustment for potential confounding factors, self-reported snoring frequency was associated with an increased risk of cardiovascular events among women but not men. The hazard ratios (95% CI) for cardiovascular events were 0.9 (0.4–2.0) for sometimes snoring and 2.5 (1.0–6.1) for everyday snoring in women and 0.7 (0.3–1.3) and 1.0 (0.5–2.1), respectively, in men. Further adjustment for body mass index attenuated the association in women; the respective hazard ratios for cardiovascular events were 0.9 (0.4–1.9) and 2.1 (0.9–5.4).<BR>Conclusions: Self-reported habitual snoring was associated with increased risk of cardiovascular events among Japanese women. Overweight may partly mediate this association.

収録刊行物

• Ｊｏｕｒｎａｌ　ｏｆ　Ｅｐｉｄｅｍｉｏｌｏｇｙ

  Ｊｏｕｒｎａｌ　ｏｆ　Ｅｐｉｄｅｍｉｏｌｏｇｙ 22 (4), 295-301, 2012

  日本疫学会

キーワード

• cardiovascular events
• obstructive sleep apnea
• population-based study
• prospective cohort study

詳細情報

• CRID: 1390001204476176896
• NII論文ID: 10030784066
• NII書誌ID: AA10952696
• DOI: 10.2188/jea.je20110109
• COI: 1:STN:280:DC%2BC38vpsVCgtQ%3D%3D
• ISSN: 13499092
• ISSN: 09175040
• PubMed: 22447210
• Web Site: https://www.jstage.jst.go.jp/article/jea/22/4/22_JE20110109/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2013173823
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可