島根県におけるつつが虫病の疫学的検討  [in Japanese] Epidemiological Study of Tsutsugamushi Disease in Shimane Prefecture, Japan  [in Japanese]

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Abstract

島根県におけるつつが虫病の病原体調査を臨床検体及び野鼠検体を用いて行った.血清抗体価による感染種推定で患者25名中23名(92%)で<i>Orientia tsutsugamushi</i> 血清型Karpの感染が考えられた.また患者の臨床検体から<i>Orientia tsutsugamushi</i> シークエンス型としてKarp 型のサブタイプであるJapanese Karp type 2(JP-2),Gilliam 型のサブタイプであるJapanese Gilliam(JG)及び韓国で報告のある<i>Orientia tsutsugamushi </i>Yeo-joo が見出された.<i>Orientia tsutsugamushi</i> Karp 型JP-2及びGilliam 型JGは県内で捕獲されたアカネズミ(<i>Apodemus speciosus</i>)からも検出されたことから,アカネズミがこれら病原体の自然界における維持に関与していることが推察された.

An epidemiological investigation into Tsutsugamushi disease in Shimane Prefecture was conducted using human clinical samples and rodent samples. A serological examination reveals <i>Orientia tsutsugamushi </i>serotype Karp as the dominant infectious serotype in patients. From sequence typing of <i>Orientia tsutsugamushi</i>, <i>Orientia tsutsugamushi </i>Japanese Karp type 2 (JP-2), Japanese Gilliam (JG), and Yeo-joo reported in Korea were detected from clinical specimens. As both JP-2 and JG types of <i>Orientia tsutsugamushi </i>have been observed in <i>Apodemus speciosus </i>in Shimane Prefecture, it is likely that <i>Apodemus speciosus </i>is the reservoir of these pathogenic <i>Orientia tsutsugamushi </i>in the natural environment.

Journal

  • Journal of the Japan Veterinary Medical Association

    Journal of the Japan Veterinary Medical Association 65(7), 535-541, 2012-07-20

    Japan Veterinary Medical Association

References:  21

Codes

  • NII Article ID (NAID)
    10030801012
  • NII NACSIS-CAT ID (NCID)
    AN00191857
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    04466454
  • NDL Article ID
    023886399
  • NDL Call No.
    Z18-352
  • Data Source
    CJP  NDL  IR  J-STAGE 
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