Advance of the Research for Disease-Responsible Genes

• Yamamoto Toshiyuki

  Tokyo Women's Medical University, Institute for Integrated Medical Sciences

Bibliographic Information

Other Title

• 疾患の責任遺伝子に関する研究の進歩

Abstract

  Over the last three decades, many disease-responsible genes have been identified due to advancement of technologies in molecular biology. Methodologies to identify disease-responsible genes have been changed according to the history. Although large subject numbers were needed previously, valuable data derived from only one rare patient have led to identify some disease-responsible genes. Recently launched next-generation sequencers have heralded the new personal genome era. We should know that we may be able to identify some disease-responsible genes by the investigation of only one patient who we meet at the bed side.

Journal

• NO TO HATTATSU

  NO TO HATTATSU 44 (4), 277-283, 2012

  The Japanese Society of Child Neurology

Keywords

• 疾患責任遺伝子
• 染色体均衡転座
• アレイCGH
• 次世代シーケンサー

Details

• CRID: 1390282680494550912
• NII Article ID: 10030801902
• NII Book ID: AN0020232X
• DOI: 10.11251/ojjscn.44.277
• ISSN: 18847668
• ISSN: 00290831
• Web Site: https://search.jamas.or.jp/link/ui/2012316142
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed