Screening botanical lactic acid bacteria with high-function isolated from product of Nagasaki prefecture for development of novel fermented foods

  • Nodake Yuichi
    Laboratory of Biochemistry, Department of Pharmacy, Faculty of Pharmaceutical Sciences, Nagasaki International University
  • Matsumoto Shuzo
    Industrial Technology Center of Nagasaki
  • Misoka Fusakazu
    Industrial Technology Center of Nagasaki
  • Tamaya Kei
    Industrial Technology Center of Nagasaki
  • Fukasawa Masashi
    Laboratory of Biochemistry, Department of Pharmacy, Faculty of Pharmaceutical Sciences, Nagasaki International University
  • Kawamura Toshiya
    Industrial Technology Center of Nagasaki
  • Sakakibara Ryuzo
    Laboratory of Biochemistry, Department of Pharmacy, Faculty of Pharmaceutical Sciences, Nagasaki International University

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Other Title
  • 長崎県内資源を活用した新規乳酸菌発酵食品開発のための高機能性植物性乳酸菌のスクリーニング
  • ナガサキ ケンナイ シゲン オ カツヨウ シタ シンキ ニュウサンキン ハッコウ ショクヒン カイハツ ノ タメ ノ コウキノウセイ ショクブツセイ ニュウサンキン ノ スクリーニング

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Abstract

  We have participated in a project that the Industrial Technology Center of Nagasaki advanced through collaboration between industry and academia and have tried to develop novel fermented biogenic foods for anti-aging and the prevention of cancer and liver disease using botanical lactic acid bacteria isolated from a product of the Nagasaki Prefecture. In this study, 620 isolated botanical lactic acid bacteria were used in the screening tests for selecting high-functional lactic acid bacteria. We obtained 219 fermented samples with an anti-oxidative activity, and 17 fermented samples were selected among them at random. As a result, 13 of the 17 fermented samples with the anti-oxidative activity suppressed the proliferation of HL60 cells and 14 fermented samples protected hepatocytes from necrosis induced by EtOH. Finally, 5 fermented samples were significantly positive in both tests. Novel foods for the maintenance and improvement of health will be developed using these high-functional botanical lactic acid bacteria in the future.

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