Respiratory Syncytial Virus 髄膜炎の1乳児例 Infantile Meningitis Caused by Respiratory Syncytial Virus

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著者

    • 諸角 美由紀 MOROZUMI Miyuki
    • 北里大学北里生命科学研究所病原微生物分子疫学研究室 Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University
    • 生方 公子 [他] UBUKATA Kimiko
    • 北里大学北里生命科学研究所病原微生物分子疫学研究室 Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University

抄録

Respiratory syncytial (RS) virus commonly causes infantile respiratory tract infection causing significant morbidity and mortality, but rarely meningitis. We report a case of meningitis caused by RS virus subgroup B in a 56-day-old boy admitted for high fever who underwent blood examination and lumbar puncture. Empirical chemotherapy was started with intravenous ampicillin, gentamicin, and cefotaxime based on laboratory data on CSF cells (84?μL) and serum CRP (13.8mg?dL) data. RS virus subgroup B was only detected using real-time PCR comprehensive reverse transcription from the first CSF, but no bacterial gene was detected. No bacteria grew from his CSF, urine, or blood. Fever and serum CRP droppedina fewdays.He had neither seizures nor disturbance of consciousness and was discharged on day 11 after admission. No evidence of encephalopathy was detected in brain MRI or electroencephalography. RS virus rarely causes meningitis, but a percentage of RS-virus-infected infants exhibit symptoms such as seizure and disturbance of consciousness. We should recognize that the RS virus may cause neurological complications associated with high morbidity and mortality.

収録刊行物

  • 感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases

    感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases 85(6), 682-685, 2011-11-20

    一般社団法人 日本感染症学会

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各種コード

  • NII論文ID(NAID)
    10030950382
  • NII書誌ID(NCID)
    AN00047715
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    03875911
  • NDL 記事登録ID
    023443354
  • NDL 請求記号
    Z19-193
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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