ANALYSIS OF REFLUX ESOPHAGITIS AND MUCOSA OF THE GASTRIC TUBE AFTER ESOPHAGECTOMY WITH GASTRIC TUBE RECONSTRUCTION

DOI 30 References
  • MOTOJIMA Ryuji
    Department of Frontier Surgery Graduate School of Medicine, Chiba University. Department of Surgery Motojima General Hospital.
  • MIYAZAKI Shinichi
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • AOKI Taito
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • NAKAJIMA Kouichi
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • OKAZAKI Yasushi
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • AKAI Takashi
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • UESATO Masaya
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • INOUE Masahito
    Department of Frontier Surgery Graduate School of Medicine, Chiba University. Department of Endoscopic Diagnostics and Therapeutics Chiba University School of Medicine.
  • HORIBE Daisuke
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • OKAZUMI Shinichi
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • SHIMADA Hideaki
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • OCHIAI Takenori
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.
  • MOTOJIMA Teiji
    Department of Surgery Motojima General Hospital.
  • MATSUBARA Hisahiro
    Department of Frontier Surgery Graduate School of Medicine, Chiba University.

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Other Title
  • 胸部食道亜全摘胃管再建症例の逆流性残食道炎と胃管粘膜の検討

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Abstract

[Purpose]The aim of this study was to determine the relationship between reflux esophagitis of residual esophagus (RE-re) and the state of the gastric mucosa and the acidity of the gastric tube of the patients who had undergone esophagectomy and gastric tube reconstruction for thoracic esophageal carcinoma. [Methods]A series of 117 patients underwent upper endoscopy, biopsy of gastric tube mucosa and the pH of the gastric tube was measured. RE-re was graded according to the Los Angeles classification System (LA grade). We measured the pH at the upper gastric tube under direct vision through an endoscope using a micro-pH glass electrode. A biopsy of the mucosa was taken from the upper part and the lower part of the gastric tube, and we assessed Helicobacter pylori (Hp) infection, mucous atrophy and intestinal metaplasia (IM). [Result]As for the cases in whom Hp infection progressed, the pH of the gastric tube was high and RE-re outbreak decreased. Similarly, as for the cases in whom atrophy and IM progressed, the pH of the gastric tube was high and RE-re outbreak decreased. [Conclusion]It was thought that RE-re had a close relationship with Hp infection and the mucosa of the gastric tube.

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