Toxicity of Poly(I:C) against Japanese Flounder <i>Paralichthys olivaceus</i>

• Matsui Takanori

  Department of Aqualife Medicine, Chonnam National University

• Oh Myung-Joo

  Department of Aqualife Medicine, Chonnam National University

• Nishizawa Toyohiko

  Department of Aqualife Medicine, Chonnam National University

Bibliographic Information

Other Title

• Poly (I:C） のヒラメに対する毒性
• Poly(I:C)ノ ヒラメ ニ タイスル ドクセイ
• Toxicity of Poly(I:C) against Japanese Flounder Paralichthys olivaceus

Abstract

We evaluated the effect of rearing temperature (13 and 17°C) on the toxicity of Poly(I:C) against Japanese flounder Paralichthys olivaceus (mean BW 8.2 g). In the fish reared at 17°C, we observed signs of toxicity such as redness or ulceration of the skin around the inoculation site or death in 41.7%, 16.7%, 16.7% and 0% of the fish injected with 800, 400, 200 and 100 μg Poly(I:C)/fish, respectively. In the fish reared at 13°C, we observed signs of toxicity in 83.3%, 75.0%, 25.0% and 33.3% of the fish that were injected with 800, 400, 200 and 100 μg Poly(I:C)/fish, respectively. Our results suggest that the toxicity of Poly(I:C) is higher in Japanese flounder reared at 13°C than in those reared at 17°C.

Journal

• Fish Pathology

  Fish Pathology 47 (3), 104-106, 2012

  The Japanese Society of Fish Pathology

Keywords

• VHSV
• live vaccine
• toxicity, Poly(I:C)
• <i>Paralichthys olivaceus</i>
• Japanese flounder

Details

• CRID: 1390282681438340096
• NII Article ID: 10031040449
• NII Book ID: AN00063165
• DOI: 10.3147/jsfp.47.104
• ISSN: 18817335
• ISSN: 0388788X
• NDL BIB ID: 024015245
• Web Site: https://agriknowledge.affrc.go.jp/RN/2010833469
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I024015245
• Text Lang: ja
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed