高脂肪食摂取ラットの脂質代謝に及ぼす乳酸発酵豆乳の効果  [in Japanese] Effects of Fermented Soymilk on Lipid Metabolism in Rats Fed a High Fat Diet  [in Japanese]

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Author(s)

    • 平畑 理映 HIRAHATA Rie
    • 武庫川女子大学大学院生活環境学研究科食物栄養学専攻 Food Science and Nutrition Major, Graduate School of Human Environmental Sciences, Mukogawa Women's University
    • 小林 麻貴 KOBAYASHI Maki
    • 武庫川女子大学生活環境学部食物栄養学科 Department of Food Science and Nutrition, School of Human Environmental Sciences, Mukogawa Women's University
    • 福田 滿 FUKUDA Mitsuru
    • 武庫川女子大学生活環境学部食物栄養学科 Department of Food Science and Nutrition, School of Human Environmental Sciences, Mukogawa Women's University

Abstract

肥満は先進国において深刻な問題であるが,脂肪エネルギー比の高い食生活が依然として続けられている.大豆食品の摂取は脂質代謝改善に効果的であることが知られている.通常食投与ラットでは乳酸発酵豆乳による脂質代謝改善効果が既報で明らかになっているので,本研究では高脂肪食投与時の乳酸発酵豆乳による効果を調べた.7週齢SD系雄性ラットをAIN-93G組成の基準飼料で1週間予備飼育後,AIN-93G組成基準食群(コントロール群,CO群),基準食の28.5%を牛脂に置換した高脂肪食群(脂肪エネルギー比60%)(HF群),高脂肪食の24.1%を乳酸発酵豆乳で置換した試験食群(飼料中大豆タンパク質10%含有)(HF-FS群)の3群(各群7匹)に分け5週間飼育した.飼育期間中に血漿脂質濃度と体脂肪量を,飼育終了後に肝臓脂質量を測定した.HF-FS群ではHS群に比べて血中TG濃度の有意な減少が認められた.また,HF-FS群ではHF群に比べて肝臓総脂質量,肝臓コレステロール量が有意に低下した.以上の結果から,高脂肪食投与ラットにおいて乳酸発酵豆乳を摂取すると,肝臓の脂質代謝を改善して血中TG濃度を低下させると推定された.

Soy foods are known to be effective for the amelioration of lipid metabolism. We investigated the effect of fermented soymilk on lipid metabolism in rats fed a high fat diet. Male Sprague-Dawley rats aged 7 weeks were fed either a control diet (AIN-93G), high fat diet including 28.5% powdered beef tallow (60% fat energy), or test diet where 24.1 % of the high fat diet was replaced with fermented soymilk (10% soy protein in diet) for 5 weeks. Although it was previously reported that the plasma triglyceride level in rats fed a normal diet (AIN-93G) was not decreased by the ingestion of fermented soymilk, it was found in the present study that the level of rats fed a high fat diet containing fermented soymilk was significantly suppressed compared with those of rats fed a high fat diet. Although the hepatic cholesterol level in rats fed a high fat diet was reduced by the ingestion of fermented soymilk, a significant decrease in plasma total cholesterol level, to the level in rats fed a normal diet, was not observed. These lipid metabolism-modulation effects in rats fed a high fat diet seem to depend on the physiological action of fermented soymilk supplemented to the diet.

Journal

  • Nippon Shokuhin Kagaku Kogaku Kaishi

    Nippon Shokuhin Kagaku Kogaku Kaishi 59(10), 528-532, 2012-10-15

    Japanese Society for Food Science and Technology

References:  16

Cited by:  2

Codes

  • NII Article ID (NAID)
    10031122188
  • NII NACSIS-CAT ID (NCID)
    AN10467499
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    1341027X
  • NDL Article ID
    024051691
  • NDL Call No.
    Z17-126
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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