GC/MSによるニコチン分析の検討と公定法との比較  [in Japanese] Examination of the Nicotine Analysis by GC/MS and a Comparison with the Regulating Method  [in Japanese]

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Author(s)

Abstract

This research examined gas chromatograph/mass spectrometer (GC/MS) measurements for nicotine and 4-ethenylpyridine, which are passive smoking markers of environmental tobacco smoke. Since the object ingredient was a polar compound, a comparison examination was performed using both a non-polar column (DB-5) and a mid-polar column (DB-17) for analysis. Of the two columns, as a result of comparing the peak shape, sensitivity, and linearity, it was found that DB-17 is suitable for measuring nicotine and 4-ethenylpyridine, which is a substitute compound of 3-ethenylpyridine. When the nicotine concentration determined by the GC/MS method was compared with that of the GC/FID method, which was the regulating method, the concentration as determined by the GC/MS method was about 30% lower than that of the GC/FID method. It was suggested that measurements by GC/FID include other organic components. When tobacco smoke (the gaseous and particle components of mainstream smoke and sidestream smoke) was measured using this GC/MS condition, nicotine was detected in all samples, except for the gaseous component of the mainstream smoke, and 3-ethenylpyridine was only detected in the gaseous component of sidestream smoke.

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 62(3), 253-257, 2013-03-05

    The Japan Society for Analytical Chemistry

References:  11

Codes

  • NII Article ID (NAID)
    10031139113
  • NII NACSIS-CAT ID (NCID)
    AN00222633
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    05251931
  • NDL Article ID
    024361363
  • NDL Call No.
    Z17-9
  • Data Source
    CJP  NDL  J-STAGE 
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