Safety and Efficacy of Implantable CardioverterDefibrillator During Pregnancy and After Delivery

  • Miyoshi Takekazu
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Kamiya Chizuko A.
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Katsuragi Shinji
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Ueda Hiroto
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Kobayashi Yoshinari
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Horiuchi Chinami
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Yamanaka Kaoru
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Neki Reiko
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Yoshimatsu Jun
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Ikeda Tomoaki
    Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
  • Yamada Yuko
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Okamura Hideo
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Noda Takashi
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Shimizu Wataru
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center

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Background: There are few studies of pregnancy and delivery in patients with an implantable cardioverter-defibrillator (ICD). The purpose of this study was to investigate maternal and fetal outcome in these patients. Methods and Results: Six pregnant women with an ICD were retrospectively reviewed. All women underwent implantation of an ICD before pregnancy and delivered at the National Cerebral and Cardiovascular Center. The mean age at pregnancy and the mean follow-up period after ICD implantation were 28±3 years old and 5±3 years, respectively. There was no device-related complication during pregnancy. In 4 women, the number of tachyarrhythmias such as non-sustained ventricular tachycardia increased after the end of the second trimester of pregnancy and anti-arrhythmic medications were gradually increased. No patient received discharges or shocks from the ICD during pregnancy, however, and only one required anti-tachycardia pacing at 27 weeks’ gestation. Mean gestational age at delivery was 37±2 weeks and all deliveries were by cesarean section, including 5 as emergency deliveries due to a fetal indication. After delivery, 2 mothers had reduced cardiac function and 1 received an ICD shock for the first time. Conclusions: Pregnancy did not increase the risk of an ICD-related complication under appropriate management. Additional caution might be required in the postpartum period as well as during pregnancy and labor.  (Circ J 2013; 77: 1166–1170)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 77 (5), 1166-1170, 2013

    一般社団法人 日本循環器学会

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