Cariotester, a new device for assessment of dentin lesion remineralization in vitro

  • UTAKA Sachiko
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • NAKASHIMA Syozi
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • SADR Alireza
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University Global COE Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo Medical and Dental University
  • IKEDA Masaomi
    Clinical Oral Science, Department of Oral Health Care Sciences, Faculty of Dentistry, Tokyo Medicaland Dental University
  • NIKAIDO Toru
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • SHIMIZU Akihiko
    Department of Dentistry and Oral Surgery, Hyogo College of Medicine
  • TAGAMI Junji
    Cariology and Operative Dentistry, Department of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University Global COE Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo Medical and Dental University

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  • Cariotester, a new device for assessment of dentin lesion remineralization <i>in vitro </i>

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This study aimed to evaluate the potential of a new device (Cariotester) for monitoring of incipient carious lesion remineralization in root dentin by topical fluoride in vitro. Demineralized bovine dentin specimens were treated by fluoride solutions (APF or neutral NaF) and remineralized for 4 weeks. Cariotester was used to measure penetration depth (CTR depth) of the indenter into the de- and remineralized specimen surface. The specimens were assessed by transverse microradiography (TMR) to determine lesion parameters (depth: LD, mineral loss: ΔZ). Pearson's correlation analysis showed an overall significant relationship between CTR depth and both TMR parameters. CTR depth appeared to distinguish the positive effect that topical fluoride application had on the remineralization of the outer zone of dentin lesions. Cariotester had the potential to serve as a quantitative tool for monitoring of incipient carious lesion remineralization in root dentin.

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