書誌事項
- タイトル別名
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- A study on involvement of metal allergy in the pathogenesis of oral lichen planus and palmoplantar pustulosis
- コウコウ ヘンペイ タイセン オヨビ ショウセキノウホウショウ ノ ハッショウ ト キンゾク アレルギー ト ノ カンレン ニ ツイテ ノ ケントウ
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Metal allergy has been considered one of the main causes of oral lichen planus (OLP) and palmoplantar pustulosis (PPP). However, the details remain poorly understood and controversial. The aim of this study was to reveal the association between these diseases and dental metal allergy.<br>Forty patients with OLP and 67 with PPP who presented at our clinic from 1992 through 2008 were studied. The presence of metal allergy confirmed by patch testing according to the ICDRG criteria. The positive rate was 45.0％ (18 of 40) in OLP and 46.3％ (31 of 67) in PPP. The rate of symptom improvement after removal of dental metal was significantly higher in PPP than in OLP (P<0.05). In PPP, symptom improvement in patients with flare-up on patch testing was significantly better after removing dental metal than that in patients without flare-up phenomenon (P<0.05).<br>These results suggest that PPP might be more closely related to dental metal allergy than OLP. In addition, removal of dental metal is demonstrated to be useful in PPP patients with flare-up.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 58 (12), 718-722, 2012
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681509753088
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- NII論文ID
- 10031156063
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 024210234
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
- KAKEN
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- 使用不可