A case of granulomatosis with polyangiitis (Wegener's granulomatosis) manifested with asymptomatic intracerebral hemorrhage
-
- TAKAOKA Hirokazu
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- HASHIMOTO Atsushi
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- NOGI Shinichi
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- IWATA Kanako
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- FUTAMI Hidekazu
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- ARINUMA Yoshiyuki
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- SHIMADA Kota
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- NAKAYAMA Hisanori
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- KOMIYA Akiko
- Department of Rheumatology, Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- FURUKAWA Hiroshi
- Department of Rheumatology, Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- MATSUI Toshihiro
- Department of Rheumatology, Sagamihara National Hospital, National Hospital Organization
-
- TOHMA Shigeto
- Department of Rheumatology, Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, National Hospital Organization
この論文をさがす
抄録
A 46-year-old man, who had had sinusitis, developed bilateral omalgia, petechiae on his lower extremities and a congested right eye. A blood test detected elevated serum C-reactive protein level. Computed tomography incidentally found an acute lesion of thalamic hemorrhage without neurological symptoms and no specific therapy was given at the time. Thereafter, he developed vertigo, vomiting and pneumonia for which antibiotics were ineffective. He was referred and admitted to our hospital. Further, aural and renal lesions, and presence of serum proteinase 3-antineutrophil cytoplasmic antibody (PR3-ANCA) confirmed his diagnosis of granulomatosis with polyangiitis (Wegener's) (GPA). With corticosteroid and cyclophosphamide therapy, his symptoms disappeared in two months along with faded PR3-ANCA. Afterward he showed neither new cerebral lesion nor symptom. This is a rare case of GPA manifested with asymptomatic intracerebral hemorrhage. It should be noted that GPA could cause various manifestations in central nervous system such as a fatal or an asymptomatic hemorrhagic lesion, which might respond to immunosuppressive therapy.<br>
収録刊行物
-
- 日本臨床免疫学会会誌
-
日本臨床免疫学会会誌 36 (1), 58-61, 2013
日本臨床免疫学会
- Tweet
キーワード
詳細情報
-
- CRID
- 1390282679629206784
-
- NII論文ID
- 10031157137
-
- NII書誌ID
- AN00357971
-
- COI
- 1:STN:280:DC%2BC3svitVSisg%3D%3D
-
- ISSN
- 13497413
- 09114300
-
- PubMed
- 23445734
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可