Activation of γ-Aminobutyrate Production by Chloroplastic H₂O₂ Is Associated with the Oxidative Stress Response

  • MARUTA Takanori
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University Department of Applied Bioscience and Biotechnology, Faculty of Life and Environmental Science, Shimane University
  • OJIRI Megumi
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University
  • NOSHI Masahiro
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University
  • TAMOI Masahiro
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University
  • ISHIKAWA Takahiro
    Department of Applied Bioscience and Biotechnology, Faculty of Life and Environmental Science, Shimane University
  • SHIGEOKA Shigeru
    Department of Advanced Bioscience, Faculty of Agriculture, Kinki University

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  • Activation of γ-Aminobutyrate Production by Chloroplastic H<sub>2</sub>O<sub>2</sub> Is Associated with the Oxidative Stress Response

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We isolated an Arabidopsis knockout line lacking glutamate decarboxylase 1 (GAD1), one that produced γ-aminobutyrate (GABA), as an oxidative stress-insensitive mutant, and found that chloroplastic H2O2 enhances GAD1 expression and GABA levels. This suggests a possible relationship between GABA metabolism and the chloroplastic H2O2-mediated stress response.

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