Low Voltage Pulse Application to Biological Cells

DOI Web Site 参考文献32件
  • OTSUKA Hidenori
    Department of Applied Chemistry, Faculty of Science, Tokyo University of Science
  • OKIMURA Saya
    Department of Applied Chemistry, Faculty of Science, Tokyo University of Science
  • NAGAMURA Masako
    Department of Applied Chemistry, Faculty of Science, Tokyo University of Science
  • MATSUKUMA Daisuke
    Department of Applied Chemistry, Faculty of Science, Tokyo University of Science
  • KUTSUZAWA Koichi
    Department of Applied Chemistry, Faculty of Science, Tokyo University of Science
  • MATSUDA Naoki
    Measurement Solution Research Center, National Institute of Advanced Industrial Science and Technology (AIST) Kyushu
  • OKABE Hirotaka
    Measurement Solution Research Center, National Institute of Advanced Industrial Science and Technology (AIST) Kyushu

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As an application of low electric field to biomedical engineering, this paper attempts to study the dose-effect of biological effects caused by msPEF with experiments on HeLa cells. MTT assay was used to trace the cell electroporation and examine cell viability. It is observed that with the increasing electric field intensity and pulse numbers, IRE effects will occur successively.

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