ヨードアレルギーを有する胆道疾患診断治療におけるガドリニウム造影剤 (ガドペンテト酸ジメグルミン) の使用経験  [in Japanese] Gadolinium as an alternative radiocontrast agent in patients with allergy to iodine-based contrast provide for useful diagnostic imagings and safely treatment of biliary tract diseases  [in Japanese]

Access this Article

Search this Article

Author(s)

Abstract

ヨードアレルギーを有する患者では胆道疾患の診断治療にヨード造影剤を使用できず,診療に難渋する.今回,MRI用造影剤であるガドペンテト酸ジメグルミンを肝内外結石,総胆管結石,胆管癌による閉塞性黄疸などの胆道疾患患者3例の診断および治療,術後のドレーン造影に対して使用し,良好な画像診断が可能であった.ガドリニウム造影剤はヨードアレルギーを有する患者における代替造影薬剤として有用と思われた.<br>

Diagnosis and treatment of biliary tract disease requires an intraductal radiocontrast agent. Although iodine-based contrast medium is commonly used, some patients show severe allergy to iodinated contrast agent. We have retrospectively reviewed the usefulness and safety of gadolinium as an alternative radiocontrast agent in 3 patients with allergy to iodine-based contrast medium in the diagnosis and treatment of biliary tract diseases. In case 1, percutaneous transhepatic biliary drainage and cholangiography were performed successfully and it was possible to visualize an intrahepatic bile duct stone. Percutaneous transhepatic cholangioscopic lithotomy was performed and the intrahepatic bile duct stone was removed. In case 2, endoscopic biliary lithotripsy was performed. In case 3, percutaneous transhepatic cholangiography and cholangioscopy provided a diagnosis of moderately differentiated carcinoma. He underwent pancreatoduodenectomy. Postoperative cholangiograms were also obtained successfully. Gadolinium contrast agent is an alternative to iodine-based cholangiography for the patients with allergy to iodine.<br>

Journal

  • Nippon Shokakibyo Gakkai Zasshi

    Nippon Shokakibyo Gakkai Zasshi 110(5), 825-832, 2013-05-05

    The Japanese Society of Gastroenterology

References:  15

Codes

Page Top