Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet
-
- OKADA Kosuke
- Division of Medical Science, Faculty of Medicine, University of Tsukuba
-
- WARABI Eiji
- Division of Biomedical Sciences, Faculty of Medicine, University of Tsukuba
-
- SUGIMOTO Hirokazu
- Department of Gastroenterology, Faculty of Medicine, The University of Tsukuba
-
- HORIE Masaki
- Division of Medical Science, Faculty of Medicine, University of Tsukuba
-
- GOTOH Naohiro
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
-
- TOKUSHIGE Katsutoshi
- Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University
-
- HASHIMOTO Etsuko
- Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University
-
- UTSUNOMIYA Hirotoshi
- Department of Strategic Surveillance for Functional Food and Comprehensive Traditional Medicine, Wakayama Medical University
-
- TAKAHASHI Hiroshi
- Department of Anesthesiology, Faculty of Medicine, University of Tsukuba
-
- ISHII Tetsuro
- Division of Biomedical Sciences, Faculty of Medicine, University of Tsukuba
-
- YAMAMOTO Masayuki
- Department of Medical Biochemistry, Tohoku University Graduate School of Medicine
-
- SHODA Junichi
- Division of Medical Science, Faculty of Medicine, University of Tsukuba
Search this Article
Author(s)
-
- OKADA Kosuke
- Division of Medical Science, Faculty of Medicine, University of Tsukuba
-
- WARABI Eiji
- Division of Biomedical Sciences, Faculty of Medicine, University of Tsukuba
-
- SUGIMOTO Hirokazu
- Department of Gastroenterology, Faculty of Medicine, The University of Tsukuba
-
- HORIE Masaki
- Division of Medical Science, Faculty of Medicine, University of Tsukuba
-
- GOTOH Naohiro
- Department of Food Science and Technology, Tokyo University of Marine Science and Technology
-
- TOKUSHIGE Katsutoshi
- Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University
-
- HASHIMOTO Etsuko
- Department of Internal Medicine and Gastroenterology, Tokyo Women's Medical University
-
- UTSUNOMIYA Hirotoshi
- Department of Strategic Surveillance for Functional Food and Comprehensive Traditional Medicine, Wakayama Medical University
-
- TAKAHASHI Hiroshi
- Department of Anesthesiology, Faculty of Medicine, University of Tsukuba
-
- ISHII Tetsuro
- Division of Biomedical Sciences, Faculty of Medicine, University of Tsukuba
-
- YAMAMOTO Masayuki
- Department of Medical Biochemistry, Tohoku University Graduate School of Medicine
-
- SHODA Junichi
- Division of Medical Science, Faculty of Medicine, University of Tsukuba
Journal
-
- Journal of gastroenterology
-
Journal of gastroenterology 48(5), 620-632, 2013-05-01
References: 37
-
1
- Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis : selected practical issues in their evaluation and management
-
VUPPALANCHI R
Hepatology 49, 306-317, 2009
Cited by (1)
-
2
- Diagnosis and therapy of nonalcoholic steatohepatitis
-
TORRES DM
Gastroenterology 134, 1682-1698, 2008
Cited by (1)
-
3
- Nonalcoholic fatty liver, steatohepatitis, and metabolic syndrome
-
MARCHESINI G
Hepatology 37, 917-923, 2003
Cited by (1)
-
4
- Molecular mediators of hepatic steatosis and liver injury
-
BROWNING JD
J Clin Invest 114, 147-152, 2004
Cited by (1)
-
5
- Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients
-
MALAGUARNERA L
J Hepatol 42, 585-591, 2005
Cited by (1)
-
6
- Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease
-
SUMIDA Y
J Hepatol 38, 32-38, 2003
Cited by (1)
-
7
- Tissue specificity of insulin resistance in humans : fat in the liver rather than muscle is associated with features of the metabolic syndrome
-
KOTRONEN A
Diabetologia 51, 130-138, 2008
Cited by (1)
-
8
- The ins and outs of mitochondrial dysfunction in NASH
-
FROMENTY B
Diabetes Metab 30, 121-138, 2004
Cited by (1)
-
9
- Mitochondrial adaptations to obesity related oxidant stress
-
YANG S
Arch Biochem Biophys 378, 259-268, 2000
Cited by (1)
-
10
- Free fatty acids promote hepatic lipotoxicity by stimulating TNF-α expression via a lysosomal pathway
-
FELDSTEIN AE
Hepatology 40, 185-194, 2004
Cited by (1)
-
11
- Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD) : a cross-sectional study
-
ALLARD JP
J Hepatol 48, 300-307, 2008
Cited by (1)
-
12
- Distinct cysteine in Keap1 are required for Keap1-dependent ubiquitination on Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
ZHANG DD
Mol Cell Biol 23, 8137-8151, 2003
Cited by (1)
-
13
- Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dithiole-3-thione
-
KWAK MK
Mol Med 7, 135-145, 2001
Cited by (1)
-
14
- Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice
-
OKADA K
Am J Physiol Gastrointest Liver Pysiol 295, G735-G747, 2008
Cited by (1)
-
15
- Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems
-
OKADA K
Biochem Biophys Res Commun 389, 431-436, 2009
Cited by (1)
-
16
- NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed high-fat diet
-
TANAKA Y
J Pharmacol Exp Ther 325, 655-664, 2008
Cited by (1)
-
17
- Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide
-
SHIN S
Eur J Pharmacol 620, 138-144, 2009
Cited by (1)
-
18
- Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defense and lipid metabolism as primary Nrf2-dependent pathways in the liver
-
KITTERINGHAM N
J Proteomics 73, 1612-1631, 2010
Cited by (1)
-
19
- Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice
-
SUGIMOTO H
Am J Physiol Gastrointest Liver Physiol 298, G283-G294, 2010
Cited by (1)
-
20
- Effects of three different highly purified n-3 series highly unsaturated fatty acids on lipid metabolism in C57BL/KsJ-db/db mice
-
GOTOH N
J Agric Food Chem 57, 11047-11054, 2009
Cited by (1)
-
21
- Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
-
MATSUZAKA T
Nat Med 13, 1193-1202, 2007
Cited by (1)
-
22
- Elovl6 : a new player in fatty acid metabolism and insulin sensitivity
-
MATSUZAKA T
J Mol Med 87, 379-384, 2009
Cited by (1)
-
23
- Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements
-
MARUYAMA A
Arch Biochem Biophys 477, 139-145, 2008
Cited by (1)
-
24
- Fatty acid transport across the cell membrane : regulation by fatty acid transporters
-
SCHWENK RW
Prostaglandins Leukot Essent Fatty Acids 82, 149-154, 2010
Cited by (1)
-
25
- Hepatic adipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice
-
TOMITA K
Hepatology 48, 458-473, 2008
Cited by (1)
-
26
- The natural history of nonalcoholic fatty liver disease : a population based cohort study
-
ADAMS LA
Gastroenterology 129, 113-121, 2005
Cited by (1)
-
27
- The plasma lipidomic signature of nonalcoholic steatohepatitis
-
PURI P
Hepatology 50, 1827-1838, 2009
Cited by (1)
-
28
- Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease
-
ARAYA J
Clin Sci 106, 635-643, 2004
Cited by (1)
-
29
- Increase in the concentration of carbon 18 monounsaturated fatty acids in the liver with hepatitis C : analysis in transgenic mice and humans
-
MORIYA K
Biochem Biophys Res Commun 281, 1207-1212, 2001
Cited by (1)
-
30
- Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice
-
FELDSTEIN A
J Hepatol 39, 978-983, 2003
Cited by (1)
-
31
- Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis
-
MAO J
Proc Natl Acad Sci USA 103, 8552-8557, 2006
Cited by (1)
-
32
- Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
NTAMBI JM
Proc Natl Acad Sci USA 99, 11482-11486, 2002
Cited by (1)
-
33
- Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis
-
MIYAZAKI M
Cell Metab 6, 484-496, 2007
Cited by (1)
-
34
- Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C
-
MIQUILENA-COLINA ME
Gut 60, 1394-1402, 2011
Cited by (1)
-
35
- Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity
-
PI J
J Biol Chem 285, 9292-9300, 2010
Cited by (1)
-
36
- Nrf2 represses FGF21 during long-term high-fat diet-induced obesity in mice
-
CHARTOUMPEKIS DV
Diabetes 60, 2465-2473, 2011
Cited by (1)
-
37
- Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet
-
Matsuzawa-Nagata Naoto , Takamura Toshinari , Kurita Seiichiro , Misu Hirofumi , Ota Tsuguhito , Ando Hitoshi , Yokoyama Masayoshi , Honda Masao , Zen Yoh , Nakanuma Yasuni , Miyamoto Kenichi , Kaneko Shuichi
Hepatology 46(5), 1392-1403, 2007-11