Air Pollution Irreversibly Impairs Lung Function: A Twenty-Year Follow-Up of Officially Acknowledged Victims in Japan
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- Yanagita Yorihide
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Senjyu Hideaki
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Asai Masaharu
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Tanaka Takako
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Yano Yudai
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Miyamoto Naomi
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Nishinakagawa Tsuyoshi
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Kotaki Kenji
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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- Kozu Ryo
- Department of Rehabilitation Medicine, Nagasaki University Hospital
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- Tabusadani Mitsuru
- Center for Industry, University and Government Cooperation, Nagasaki University
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- Honda Sumihisa
- Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Science
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Lung function is one of the strongest determinants of cardiopulmonary health and longevity. Long-term exposure to air pollution has been associated with decreased lung function. We undertook a retrospective study to compare the long-term consequences of air pollution in two areas of Japan: Mizushima, Okayama Prefecture and Kitakyushu, Fukuoka Prefecture. Industrialization began in Mizushima in the 1940s, whereas it began in Kitakyushu in the early 1900s. In Kitakyushu, levels of nitrogen dioxide have been higher compared to the Mizushima area. The subjects comprised 623 officially acknowledged victims of pollution-related illness (489 from Mizushima and 134 from Kitakyushu). All subjects were lifetime non-smokers and aged 65 years or older at the time of their last medical examination in 2009. Demographic data including diagnosed lung diseases and lung function at the time of certification assessment performed between 1973 and 1988 were obtained. The subjects from Kitakyushu were significantly younger (47.1 vs. 51.0 years, p < 0.001) and a higher percentage had asthma (91.2 vs. 36.8%, p < 0.001) compared to those from Mizushima. Furthermore, all measures of lung function were significantly lower in Kitakyushu group at the time of the certification assessment (p < 0.001) and at the follow-up (p < 0.001). However, no significant differences were observed in the annual mean decline in lung function between the two groups, despite the overall decrease in air pollution. In conclusion, the normal lung function is not restored even after improvement of air pollution. It is essential for every city to prevent air pollution.
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 230 (3), 177-184, 2013
東北ジャーナル刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282679219401344
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- NII論文ID
- 10031189113
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- NII書誌ID
- AA00863920
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- COI
- 1:STN:280:DC%2BC3sfhsVyiug%3D%3D
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- ISSN
- 13493329
- 00408727
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- HANDLE
- 10069/33882
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- PubMed
- 23863333
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可