Noninvasive and Simple Assessment of Cardiac Output and Pulmonary Vascular Resistance With Whole-Body Impedance Cardiography Is Useful for Monitoring Patients With Pulmonary Hypertension
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- Taniguchi Yu
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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- Emoto Noriaki
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine Clinical Pharmacy, Kobe Pharmaceutical University
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- Miyagawa Kazuya
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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- Nakayama Kazuhiko
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine Clinical Pharmacy, Kobe Pharmaceutical University
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- Kinutani Hiroto
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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- Tanaka Hidekazu
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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- Shinke Toshiro
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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- Hirata Ken-ichi
- Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
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Background: Right heart catheterization (RHC) is the gold standard for the diagnosis of pulmonary hypertension (PH) and a useful tool for monitoring PH. However, there are some disadvantages in the regular use of RHC because it is invasive. Noninvasive methods for monitoring hemodynamics are needed to manage patients with PH. In this study, we aimed to evaluate the reliability of noninvasive hemodynamic assessment with whole-body impedance cardiography (Non-Invasive Cardiac System [NICaS]) for PH. Methods and Results: We investigated 65 consecutive patients undergoing RHC. Two-thirds of them had pulmonary arterial hypertension and one-third had chronic thromboembolic PH; 25% of the patients were receiving medical therapy. Cardiac output (CO) was estimated by NICaS (NI-CO), thermodilution (TD-CO), and the Fick method (Fick-CO). There was a strong correlation between NI-CO and TD-CO (r=0.715, P<0.0001) and Fick-CO (r=0.653, P<0.0001). Noninvasive pulmonary vascular resistance (PVR) was estimated using a conventional invasive equation with NI-CO, mean pulmonary arterial pressure was calculated by echocardiographic measurement, and pulmonary capillary wedge pressure was estimated at 10mmHg in all cases. NICaS-derived PVR was very strongly correlated with invasive PVR (TD-PVR: r=0.704, P<0.0001; Fick-PVR: r=0.702, P<0.0001). Conclusions: Noninvasive measurement of CO and PVR using NICaS and echocardiography is a useful tool for the assessment of PH. (Circ J 2013; 77: 2383–2389)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 77 (9), 2383-2389, 2013
一般社団法人 日本循環器学会
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詳細情報
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- CRID
- 1390282680080471808
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- NII論文ID
- 10031191768
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- NII書誌ID
- AA11591968
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- COI
- 1:STN:280:DC%2BC3sjhtlaqsA%3D%3D
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- ISSN
- 13474820
- 13469843
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- PubMed
- 23759655
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- PubMed
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