Award Review : Fermentative Production of Plant Benzylisoquinoline Alkaloids in Microbes
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- MINAMI Hiromichi
- Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University
書誌事項
- タイトル別名
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- Fermentative Production of Plant Benzylisoquinoline Alkaloids in Microbes
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Higher plants produce diverse chemicals, including alkaloids, terpenoids, and phenolic compounds (phenylpropanoids and flavonoids) as secondary metabolites. These chemicals are widely used for human health and nutrition. Alkaloids, for example, are valued in medicine due to their high biological activities, but most of these metabolites accumulate at low levels in plant cells, resulting in poor extraction yields. Increasingly, attention is devoted to the production of plant metabolites by reconstructing plant biosynthetic pathways in microorganisms. This technology has been aided by advances in synthetic biology and metabolic engineering. Here, the review a fermentation platform for low-cost production of numerous alkaloids using bioengineered Escherichia coli and/or Saccharomyces cerevisiae.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 77 (8), 1617-1622, 2013
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681455401216
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- NII論文ID
- 10031195806
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- NII書誌ID
- AA10824164
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- COI
- 1:STN:280:DC%2BC3sfns1Ontg%3D%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 024791533
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- PubMed
- 23924710
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可