培養骨格筋のバイオアクチュエータへの応用

DOI Web Site 被引用文献1件 参考文献8件
  • 中尾 誠
    大阪工業大学大学院工学研究科生体医工学専攻
  • 赤土 和也
    大阪工業大学大学院工学研究科機械工学専攻
  • 山崎 健一
    大阪工業大学大学院工学研究科生体医工学専攻
  • 寺田 堂彦
    大阪工業大学大学院工学研究科生体医工学専攻 ヒューマンサイエンス振興財団
  • 藤里 俊哉
    大阪工業大学大学院工学研究科生体医工学専攻
  • 吉浦 昌彦
    大阪工業大学大学院工学研究科生体医工学専攻
  • 筒井 博司
    大阪工業大学大学院工学研究科生体医工学専攻

書誌事項

タイトル別名
  • Application of Cultivated Skeletal Muscle to Bio-actuator
  • バイヨウ コッカクキン ノ バイオアクチュエータ エ ノ オウヨウ

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抄録

If we regard skeletal muscle as an actuator, we see it has excellent flexibility and efficiency, properties that artificial actuators such as electric motors or mechanical engines do not have. We have been researching the creation of miniaturized bio-actuators that use cultured skeletal muscle. We reported that stimulation was very important to culture myoblast and to develop skeletal muscle. We obtained skeletal muscle by cultivating C2C12 cells using unidirectional mechanical stimulation. We developed a Bio-Actuator System as a mode for a skeletal muscle system in which this cultured skeletal muscle was used as actuator unit. This Bio-Actuator System was made to imitate the musculoskeletal system and consisted of one joint, two arms, one flexor muscle and one extensor muscle. One arm was fixed on the base, and the other arm was able to rotate freely about the joint axis. Because skeletal muscle can only contract, we used cultured skeletal muscle as flexor muscle and sliced silicon elastic sheet as extensor muscle. Experiments were conducted with this Bio-Actuator System in a culture medium. By applying pulsed voltage to the culture medium, the bio-actuator unit was contracted and relaxed. By repeating these contractions and expansions, we observed that the tip of the arm vibrated periodically.

収録刊行物

  • 生体医工学

    生体医工学 47 (6), 560-565, 2009

    公益社団法人 日本生体医工学会

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