Estimation of Perilymph Enhancement after Intratympanic Administration of Gd-DTPA by Fast T<sub>1</sub>-mapping with a Dual Flip Angle 3D Spoiled Gradient Echo Sequence

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  • NAGANAWA Shinji
    Department of Radiology, Nagoya University Graduate School of Medicine
  • YAMAZAKI Masahiro
    Department of Radiology, Nagoya University Graduate School of Medicine
  • KAWAI Hisashi
    Department of Radiology, Nagoya University Graduate School of Medicine
  • BOKURA Kiminori
    Department of Radiology, Nagoya University Graduate School of Medicine
  • SONE Michihiko
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine
  • NAKASHIMA Tsutomu
    Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine

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  • Estimation of Perilymph Enhancement after Intratympanic Administration of Gd-DTPA by Fast T1-mapping with a Dual Flip Angle 3D Spoiled Gradient Echo Sequence

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Abstract

Eleven patients with suspected Ménière's disease received intratympanic (IT) administration of gadolinium (gadopentetate dimeglumine; Gd) prior to acquisition of 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR), 3D real inversion recovery (IR), and fast T1 mapping by dual flip angle 3D gradient echo (FT1-map) imaging sequences to evaluate the degree of perilymph enhancement. Though 3-dimensional FLAIR could detect lower concentrations of gadolinium than 3D real IR, in 2 patients, poor enhancement still prevented visualization of the endolymphatic space using 3D FLAIR. We could predict poor contrast enhancement in these 2 patients using the FT1-map technique.<br>

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